View source for (-)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)

{{Infobox enzyme
| Name = Presilphiperfolanol synthase
| EC_number = 4.2.3.74
| CAS_number = 
| IUBMB_EC_number = 4/2/3/74
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Presilphiperfolanol synthase''' ({{EC number|4.2.3.74}}, ''BcBOT2, CND15'') is an [[enzyme]] with system name ''(2E,6E)-farnesyl-diphosphate diphosphohydrolase (presilphiperfolan-8beta-ol-forming)''.<ref>{{cite journal | title = Sesquiterpene synthase from the botrydial biosynthetic gene cluster of the phytopathogen <em>Botrytis cinerea</em> |author = Pinedo, C., Wang, C.M., Pradier, J.M., Dalmais, B., Choquer, M., Le Pecheur, P., Morgant, G., Collado, I.G., Cane, D.E. and Viaud, M. |journal = ACS Chem. Biol. |date = 2008 |volume = 3 |pages = 791-801 |pmid = 19035644}}</ref><ref>{{cite journal | title = Biosynthesis of the sesquiterpene botrydial in <em>Botrytis cinerea</em>. Mechanism and stereochemistry of the enzymatic formation of  presilphiperfolan-8&beta;-ol |author = Wang, C.M., Hopson, R., Lin, X. and Cane, D.E. |journal = J. Am. Chem. Soc. |date = 2009 |volume = 131 |pages = 8360-8361 |pmid = 19476353}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (2E,6E)-farnesyl diphosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> presilphiperfolan-8beta-ol + [[diphosphate]]

This enzyme requires Mg<sup>2+</sup>. 

== References ==
{{reflist}}

== External links ==
* {{MeshName|Presilphiperfolanol+synthase}}

[[Category:EC 4.2.3]]