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{{enzyme
| Name = 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
| EC_number = 2.1.1.116
| CAS_number = 132084-81-2
| IUBMB_EC_number = 2/1/1/116
| GO_code = 0030784
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase''' ({{EC number|2.1.1.116}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + (S)-reticuline

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[3'-hydroxy-N-methyl-(S)-coclaurine]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[(S)-reticuline]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases.  The systematic name of this enzyme class is '''S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase'''. This enzyme participates in [[alkaloid biosynthesis i]].  

==References==
{{reflist|1}}
* {{cite journal | author = Frenzel T, Zenk MH | date = 1990 | title = S-Adenosyl-L-methionine: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase, a regio- and stereoselective enzyme of the (S)-reticuline pathway | journal = [[Phytochemistry (journal)|Phytochemistry]]  | volume = 29 | pages = 3505&ndash;3511 | doi = 10.1016/0031-9422(90)85265-H | issue = 11 }}

[[Category:EC 2.1.1]]
[[Category:Enzymes of unknown structure]]

{{transferase-stub}}