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{{Infobox enzyme
| Name = Levopimaradiene synthase
| EC_number = 4.2.3.32
| CAS_number = 
| IUBMB_EC_number = 4/2/3/32
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Levopimaradiene synthase''' ({{EC number|4.2.3.32}}, ''PtTPS-LAS'', ''LPS'', ''copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]'') is an [[enzyme]] with system name ''(+)-copalyl-diphosphate diphosphate-lyase (abieta-8(14),12-diene-forming)''.<ref>{{cite journal | title = Cloning and characterization of <em>Ginkgo biloba</em> levopimaradiene synthase which catalyzes the first committed step in ginkgolide biosynthesis |author = Schepmann, H.G., Pang, J. and Matsuda, S.P. |journal = Arch. Biochem. Biophys. |year = 2001 |volume = 392 |pages = 263–269 |pmid = 11488601 |doi=10.1006/abbi.2001.2438 |issue=2}}</ref><ref>{{cite journal | title = Diterpene resin acid biosynthesis in loblolly pine (<em>Pinus taeda</em>): functional characterization of abietadiene/levopimaradiene synthase  (PtTPS-LAS) cDNA and subcellular targeting of PtTPS-LAS and  abietadienol/abietadienal oxidase (PtAO, CYP720B1) |author = Ro, D.K. and Bohlmann, J. |journal = Phytochemistry |year = 2006 |volume = 67 |pages = 1572–1578 |pmid = 16497345 |doi=10.1016/j.phytochem.2006.01.011}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (+)-copalyl diphosphate <math>\rightleftharpoons</math> abieta-8(14),12-diene + [[diphosphate]]

In [[Ginkgo]], the enzyme catalyses the initial cyclization step in the biosynthesis of [[ginkgolides]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Levopimaradiene+synthase}}

[[Category:EC 4.2.3]]