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{{Infobox enzyme
| Name = 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
| EC_number = 3.7.1.14
| CAS_number = 
| IUBMB_EC_number = 3/7/1/14
| GO_code = 
| image = 
| width = 
| caption =
}}
'''2-hydroxy-6-oxonona-2,4-dienedioate hydrolase''' ({{EC number|3.7.1.14}}, ''mhpC (gene)'') is an [[enzyme]] with system name ''(2Z,4E)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase''.<ref>{{cite journal | title = Catabolism of phenylpropionic acid and its 3-hydroxy derivative by ''Escherichia coli'' |author = Burlingame, R. and Chapman, P.J. |journal = J. Bacteriol. |year = 1983 |volume = 155 |pages = 113–121 |pmid = 6345502 | issue = 1 | pmc = 217659}}</ref><ref>{{cite journal | title = Isolation and characterization of ''Escherichia coli'' mutants defective for phenylpropionate degradation |author = Burlingame, R.P., Wyman, L. and Chapman, P.J. |journal = J. Bacteriol. |year = 1986 |volume = 168 |pages = 55–64 |pmid = 3531186 | issue = 1 | pmc = 213419}}</ref><ref>{{cite journal | title = Chemistry of extradiol aromatic ring cleavage: isolation of a stable dienol ring fission intermediate and stereochemistry of its enzymatic hydrolytic clevage |author = Lam, W. W. Y and Bugg, T. D. H. |journal = J. Chem. Soc., Chem. Commun. |year = 1994 |volume = 10 |pages = 1163–1164 |pmid = | doi = 10.1039/c39940001163 | issue = 10 }}</ref><ref>{{cite journal | title = Purification, characterization, and stereochemical analysis of a C-C hydrolase: 2-hydroxy-6-keto-nona-2,4-diene-1,9-dioic acid 5,6-hydrolase |author = Lam, W.W. and Bugg, T.D. |journal = Biochemistry |year = 1997 |volume = 36 |pages = 12242–12251 |pmid = 9315862 | doi = 10.1021/bi971115r | issue = 40}}</ref><ref>{{cite journal | title = Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of ''Escherichia coli'' K-12 |author = Ferr&aacute;ndez, A., Garc&iacute;a, J.L. and D&iacute;az, E. |journal = J. Bacteriol. |year = 1997 |volume = 179 |pages = 2573–2581 |pmid = 9098055 | issue = 8 | pmc = 179006}}</ref><ref>{{cite journal | title = Characterization of the ''hca'' cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in ''Escherichia coli'' K-12 |author = D&iacute;az, E., Ferr&aacute;ndez, A. and Garc&iacute;a, J.L. |journal = J. Bacteriol. |year = 1998 |volume = 180 |pages = 2915–2923 |pmid = 9603882 | issue = 11 | pmc = 107259}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (1) (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H<sub>2</sub>O <math>\rightleftharpoons</math> (2Z)-2-hydroxypenta-2,4-dienoate + [[succinate]]
: (2) (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H<sub>2</sub>O <math>\rightleftharpoons</math> (2Z)-2-hydroxypenta-2,4-dienoate + [[fumarate]]

This enzyme catalyses a step in a pathway of [[phenylpropanoid]] compounds degradation.

== References ==
{{reflist}}

== External links ==
*{{MeshName|2-hydroxy-6-oxonona-2,4-dienedioate+hydrolase}}

[[Category:EC 3.7.1]]