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{{Infobox enzyme
| Name = Chanoclavine-I dehydrogenase
| EC_number = 1.1.1.332
| CAS_number = 
| IUBMB_EC_number = 1/1/1/332
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Chanoclavine-I dehydrogenase''' ({{EC number|1.1.1.332}}, ''easD (gene)'', ''fgaDH (gene)'') is an [[enzyme]] with system name ''chanoclavine-I:NAD<sup>+</sup> oxidoreductase''.<ref>{{cite journal | title = Ergot alkaloid biosynthesis in <em>Aspergillus fumigatus</em>: conversion of chanoclavine-I to chanoclavine-I aldehyde catalyzed by a short-chain alcohol dehydrogenase FgaDH |author = Wallwey, C., Matuschek, M. and Li, S.M. |journal = Arch. Microbiol. |year = 2010 |volume = 192 |pages = 127–134 |pmid = 20039019 |doi=10.1007/s00203-009-0536-1 |issue=2}}</ref><ref>{{cite journal | title = Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae |author = Wallwey, C., Heddergott, C., Xie, X., Brakhage, A.A. and Li, S.M. |journal = Microbiology |year = 2012 |volume = 158 |pages = 1634–1644 |pmid = 22403186 |doi=10.1099/mic.0.056796-0 |issue=Pt 6}}</ref> This enzyme [[catalysis|catalises]] the following [[chemical reaction]]

: [[chanoclavine]]-I + NAD<sup>+</sup> <math>\rightleftharpoons</math> chanoclavine-I aldehyde + NADH + H<sup>+</sup>

This enzyme catalyses a step in the pathway of [[ergot alkaloid]] biosynthesis in certain fungi.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Chanoclavine-I+dehydrogenase}}

[[Category:EC 1.1.1]]