View source for Branched-chain-2-oxoacid decarboxylase

{{enzyme
| Name = dehydro-L-gulonate decarboxylase
| EC_number = 4.1.1.34
| CAS_number = 9024-67-3
| IUBMB_EC_number = 4/1/1/34
| GO_code = 0047842
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''dehydro-L-gulonate decarboxylase''' ({{EC number|4.1.1.34}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:3-dehydro-L-gulonate <math>\rightleftharpoons</math> L-xylulose + CO<sub>2</sub>

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[3-dehydro-L-gulonate]], and two [[product (chemistry)|products]], [[L-xylulose]] and [[carbon dioxide|CO<sub>2</sub>]].

This enzyme belongs to the family of [[lyase]]s, specifically the carboxy-lyases, which cleave carbon-carbon bonds.  The systematic name of this enzyme class is '''3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)'''. Other names in common use include '''keto-L-gulonate decarboxylase''', '''3-keto-L-gulonate decarboxylase''', and '''3-dehydro-L-gulonate carboxy-lyase'''.  This enzyme participates in [[pentose and glucuronate interconversions]].  

==References==
{{reflist|1}}
* {{cite journal | author = Smiley JD and Ashwell G | date = 1961 | title = Purification and properties of beta-L-hydroxy acid dehydrogenase II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis | journal = J. Biol. Chem.  | volume = 236 | pages = 357&ndash;364 }}

{{4.1-enzyme-stub}}

[[Category:EC 4.1.1]]
[[Category:Enzymes of unknown structure]]