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{{Infobox enzyme
| Name = Ent-kaurenoic acid oxidase
| EC_number = 1.14.13.79
| CAS_number = 337507-95-6
| IUBMB_EC_number = 1/14/13/79
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Ent-kaurenoic acid oxidase''' ({{EC number|1.14.13.79}}) is an [[enzyme]] with system name ''ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | title = The CYP88A cytochrome P450, <em>ent</em>-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway |author = Helliwell, C.A., Chandler, P.M., Poole, A., Dennis, E.S. and Peacock, W.J. |journal = Proc. Natl. Acad. Sci. USA |year = 2001 |volume = 98 |pages = 2065–2070 |pmid = 11172076 |doi=10.1073/pnas.041588998 |issue=4 |pmc=29382}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: ent-kaur-16-en-19-oate + 3 NADPH + 3 H<sup>+</sup> + 3 O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin A12 + 3 NADP<sup>+</sup> + 4 H<sub>2</sub>O (overall reaction)
:(1a) ent-kaur-16-en-19-oate + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> ent-7alpha-hydroxykaur-16-en-19-oate + NADP<sup>+</sup> + H<sub>2</sub>O
:(1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin A12 aldehyde + NADP<sup>+</sup> + 2 H<sub>2</sub>O
:(1c) gibberellin A12 aldehyde + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> gibberellin A12 + NADP<sup>+</sup> + H<sub>2</sub>O

Ent-kaurenoic acid oxidase requires [[cytochrome P450]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Ent-kaurenoic+acid+oxidase}}

[[Category:EC 1.14.13]]