View source for Demethylrebeccamycin-D-glucose O-methyltransferase

{{Infobox enzyme
| Name = 16S rRNA (cytosine<sup>967</sup>-C<sup>5</sup>)-methyltransferase
| EC_number = 2.1.1.176
| CAS_number = 
| IUBMB_EC_number = 2/1/1/176
| GO_code = 
| image = 
| width = 
| caption =
}}
'''16S rRNA (cytosine<sup>967</sup>-C<sup>5</sup>)-methyltransferase''' ({{EC number|2.1.1.176}}, ''rsmB (gene)'', ''fmu (gene)'', ''16S rRNA m5C967 methyltransferase'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:16S rRNA (cytosine<sup>967</sup>-C<sup>5</sup>)-methyltransferase''.<ref>{{cite journal | title = Purification, cloning, and characterization of the 16S RNA m<sup>5</sup>C<sup>967</sup> methyltransferase from ''Escherichia coli'' |author = Tscherne, J.S., Nurse, K., Popienick, P., Michel, H., Sochacki, M. and Ofengand, J. |journal = Biochemistry |year = 1999 |volume = 38 |pages = 1884–1892 |pmid = 10026269}}</ref><ref>{{cite journal | title = Identification of the 16S rRNA m<sup>5</sup>C<sup>967</sup> methyltransferase from ''Escherichia coli'' |author = Gu, X.R., Gustafsson, C., Ku, J., Yu, M. and Santi, D.V. |journal = Biochemistry |year = 1999 |volume = 38 |pages = 4053–4057 |pmid = 10194318}}</ref><ref>{{cite journal | title = The first structure of an RNA m<sup>5</sup>C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate |author = Foster, P.G., Nunes, C.R., Greene, P., Moustakas, D. and Stroud, R.M. |journal = Structure |year = 2003 |volume = 11 |pages = 1609–1620 |pmid = 14656444}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[S-adenosyl-L-methionine]] + [[cytosine]]<sup>967</sup> in [[Ribosomal RNA|16S rRNA]] <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + [[5-methylcytosine]]<sup>967</sup> in 16S rRNA

The enzyme specifically methylates cytosine<sup>967</sup> at C<sup>5</sup> in 16S rRNA.

== References ==
{{reflist}}

== External links ==
* {{MeshName|16S+rRNA+(cytosine967-C5)-methyltransferase}}

[[Category:EC 2.1.1]]