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{{Infobox enzyme
| Name = Nitric oxide reductase (NAD(P), nitrous oxide-forming)
| EC_number = 1.7.1.14
| CAS_number = 
| IUBMB_EC_number = 1/7/1/14
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Nitric oxide reductase (NAD(P), nitrous oxide-forming)''' ({{EC number|1.7.1.14}}, ''fungal nitric oxide reductase'', ''cytochrome P450nor'', ''NOR (ambiguous)'') is an [[enzyme]] with system name ''nitrous oxide:NAD(P) oxidoreductase''.<ref>{{cite journal | title = Denitrification by the fungus ''Fusarium oxysporum'' and involvement of cytochrome ''P''-450 in the respiratory nitrite reduction |author = Shoun, H. and Tanimoto, T. |journal = J. Biol. Chem. |year = 1991 |volume = 266 |pages = 11078–11082 |pmid = 2040619 |issue=17}}</ref><ref>{{cite journal | title = Spectroscopic and kinetic studies on reaction of cytochrome ''P''<sub>450</sub>nor with nitric oxide. Implication for its nitric oxide reduction mechanism |author = Shiro, Y., Fujii, M., Iizuka, T., Adachi, S., Tsukamoto, K., Nakahara, K. and Shoun, H. |journal = J. Biol. Chem. |year = 1995 |volume = 270 |pages = 1617–1623 |pmid = 7829493 |issue=4}}</ref><ref>{{cite journal | title = The B&prime; helix determines cytochrome ''P''<sub>450</sub>nor specificity for the electron donors NADH and NADPH |author = Zhang, L., Kudo, T., Takaya, N. and Shoun, H. |journal = J. Biol. Chem. |year = 2002 |volume = 277 |pages = 33842–33847 |pmid = 12105197 |doi=10.1074/jbc.M203923200}}</ref><ref>{{cite journal | title = Structural evidence for direct hydride transfer from NADH to cytochrome ''P''<sub>450</sub>nor |author = Oshima, R., Fushinobu, S., Su, F., Zhang, L., Takaya, N. and Shoun, H. |journal = J. Mol. Biol. |year = 2004 |volume = 342 |pages = 207–217 |pmid = 15313618 |doi=10.1016/j.jmb.2004.07.009}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: N<sub>2</sub>O + NAD(P)<sup>+</sup> + H2O <math>\rightleftharpoons</math> 2 NO + NAD(P)H + H<sup>+</sup>

This enzyme is heme-thiolate protein (P450).

== References ==
{{reflist}}

== External links ==
* {{MeshName|Nitric+oxide+reductase+(NAD(P),+nitrous+oxide-forming)}}

[[Category:EC 1.7.1]]