View source for Hydroxynitrilase

{{enzyme
| Name = malyl-CoA lyase
| EC_number = 4.1.3.24
| CAS_number = 37290-67-8
| IUBMB_EC_number = 4/1/3/24
| GO_code = 0050083
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''malyl-CoA lyase''' ({{EC number|4.1.3.24}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:(3S)-3-carboxy-3-hydroxypropanoyl-CoA <math>\rightleftharpoons</math> acetyl-CoA + glyoxylate

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[(3S)-3-carboxy-3-hydroxypropanoyl-CoA]], and two [[product (chemistry)|products]], [[acetyl-CoA]] and [[glyoxylate]].

This enzyme belongs to the family of [[lyase]]s, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds.  The systematic name of this enzyme class is '''(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)'''. Other names in common use include '''malyl-coenzyme A lyase''', and '''(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase'''.  This enzyme participates in [[glyoxylate and dicarboxylate metabolism]].  

==References==
{{reflist|1}}
* {{cite journal | author = Tuboi S and Kikuchi G | date = 1965 | title = Enzymic cleavage of malyl-Coenzyme A into acetyl-Coenzyme A and glyoxylic acid | journal = Biochim. Biophys. Acta  | volume = 96 | pages = 148&ndash;153 }}

{{4.1-enzyme-stub}}

[[Category:EC 4.1.3]]
[[Category:Enzymes of unknown structure]]