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{{Infobox enzyme
| Name = Gamma-humulene synthase
| EC_number = 4.2.3.56
| CAS_number = 110639-19-5
| IUBMB_EC_number = 4/2/3/56
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Gamma-humulene synthase''' ({{EC number|4.2.3.56}}, ''humulene cyclase'') is an [[enzyme]] with system name ''(2E,6E)-farnesyl-diphosphate diphosphate-lyase (gamma-humulene-forming)''.<ref>{{cite journal | title = Sesquiterpene synthases from grand fir (<em>Abies grandis</em>). Comparison of constitutive and wound-induced activities, and cDNA isolation,  characterization, and bacterial expression of &delta;-selinene synthase and  &gamma;-humulene synthase |author = Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. |journal = J. Biol. Chem. |year = 1998 |volume = 273 |pages = 2078–2089 |pmid = 9442047 |doi=10.1074/jbc.273.4.2078}}</ref><ref>{{cite journal | title = Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases &delta;-selinene synthase and  &gamma;-humulene synthase |author = Little, D.B. and Croteau, R.B. |journal = Arch. Biochem. Biophys. |year = 2002 |volume = 402 |pages = 120–135 |pmid = 12051690 |doi=10.1016/S0003-9861(02)00068-1 |issue=1}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (2E,6E)-farnesyl diphosphate <math>\rightleftharpoons</math> gamma-humulene + [[diphosphate]]

== References ==
{{reflist}}

== External links ==
* {{MeshName|Gamma-humulene+synthase}}

[[Category:EC 4.2.3]]