View source for L-olivosyl-oleandolide 3-O-methyltransferase

{{Infobox enzyme
| Name = Trimethylamine-corrinoid protein Co-methyltransferase
| EC_number = 2.1.1.250
| CAS_number = 
| IUBMB_EC_number = 2/1/1/250
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Trimethylamine-corrinoid protein Co-methyltransferase''' ({{EC number|2.1.1.250}}, ''mttB (gene)'', ''trimethylamine methyltransferase'') is an [[enzyme]] with system name ''trimethylamine:5-hydroxybenzimidazolylcobamide Co-methyltransferase''.<ref>{{cite journal | title = Reconstitution of trimethylamine-dependent coenzyme M methylation with the trimethylamine corrinoid protein and the isozymes of methyltransferase II from <em>Methanosarcina barkeri</em> |author = Ferguson, D.J., Jr. and Krzycki, J.A. |journal = J. Bacteriol. |date = 1997 |volume = 179 |pages = 846-852 |pmid = 9006042}}</ref><ref>{{cite journal | title = Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases |author = Krzycki, J.A. |journal = Curr. Opin. Chem. Biol. |date = 2004 |volume = 8 |pages = 484-491 |pmid = 15450490}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[trimethylamine]] + [Co(I) trimethylamine-specific corrinoid protein] <math>\rightleftharpoons</math> [methyl-Co(III) trimethylamine-specific corrinoid protein] + [[dimethylamine]]

This enzyme is involved in methanogenesis from trimethylamine.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Trimethylamine---corrinoid+protein+Co-methyltransferase}}

[[Category:EC 2.1.1]]