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{{Infobox enzyme
| Name = Very-long-chain acyl-CoA dehydrogenase
| EC_number = 1.3.8.9
| CAS_number = 
| IUBMB_EC_number = 1/3/8/9
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Very-long-chain acyl-CoA dehydrogenase''' ({{EC number|1.3.8.9}}, ''ACADVL (gene).'') is an [[enzyme]] with system name ''very-long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase''.<ref>{{cite journal | title = Novel fatty acid &beta;-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase |author = Izai, K., Uchida, Y., Orii, T., Yamamoto, S. and Hashimoto, T. |journal = J. Biol. Chem. |year = 1992 |volume = 267 |pages = 1027–1033 |pmid = 1730632 |issue=2}}</ref><ref>{{cite journal | title = Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients |author = Aoyama, T., Souri, M., Ushikubo, S., Kamijo, T., Yamaguchi, S., Kelley, R.I., Rhead, W.J., Uetake, K., Tanaka, K. and Hashimoto, T. |journal = J. Clin. Invest. |year = 1995 |volume = 95 |pages = 2465–2473 |pmid = 7769092 |doi=10.1172/JCI117947 |issue=6 |pmc=295925}}</ref><ref>{{cite journal | title = Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase |author = McAndrew, R.P., Wang, Y., Mohsen, A.W., He, M., Vockley, J. and Kim, J.J. |journal = J. Biol. Chem. |year = 2008 |volume = 283 |pages = 9435–9443 |pmid = 18227065 |doi=10.1074/jbc.M709135200 |issue=14 |pmc=2431035}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: a very-long-chain [[acyl-CoA]] + electron-transfer [[flavoprotein]] <math>\rightleftharpoons</math> a very-long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein

This enzyme contains FAD as [[prosthetic group]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Very-long-chain+acyl-CoA+dehydrogenase}}

[[Category:EC 1.3.8]]