View source for Rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,3/1,4-galactofuranosyltransferase

{{Infobox enzyme
| Name = TRNA-guanine15 transglycosylase
| EC_number = 2.4.2.48
| CAS_number = 
| IUBMB_EC_number = 2/4/2/48
| GO_code = 
| image = 
| width = 
| caption =
}}
'''TRNA-guanine15 transglycosylase''' ({{EC number|2.4.2.48}}, ''tRNA transglycosylase'', ''transfer ribonucleate glycosyltransferase'', ''tRNA guanine15 transglycosidase'', ''TGT'', ''transfer ribonucleic acid guanine15 transglycosylase'') is an [[enzyme]] with system name ''tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase''.<ref>{{cite journal | title = Hypermodification of tRNA in thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from ''Methanococcus jannaschii'' |author = Bai, Y., Fox, D.T., Lacy, J.A., Van Lanen, S.G. and Iwata-Reuyl, D. |journal = J. Biol. Chem. |year = 2000 |volume = 275 |pages = 28731–28738 |pmid = 10862614 | doi = 10.1074/jbc.M002174200 | issue = 37}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[guanine]]<sup>15</sup> in tRNA + 7-cyano-7-carbaguanine <math>\rightleftharpoons</math> 7-cyano-7-carbaguanine15 in tRNA + [[guanine]]

[[Archaeal]] [[Transfer RNA|tRNAs]] contain the modified [[nucleoside]] [[archaeosine]] at position 15.

== References ==
{{reflist}}

== External links ==
*{{MeshName|TRNA-guanine15+transglycosylase}}

[[Category:EC 2.4.2]]