View source for Trans-hexaprenyltranstransferase

{{enzyme
| Name = Z-farnesyl diphosphate synthase
| EC_number = 2.5.1.68
| CAS_number = 
| IUBMB_EC_number = 2/5/1/68
| GO_code = 
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''Z-farnesyl diphosphate synthase''' ({{EC number|2.5.1.68}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:geranyl diphosphate + isopentenyl diphosphate <math>\rightleftharpoons</math> diphosphate + (2Z,6E)-farnesyl diphosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[geranyl diphosphate]] and [[isopentenyl diphosphate]], whereas its two [[product (chemistry)|products]] are [[diphosphate]] and [[(2Z,6E)-farnesyl diphosphate]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring aryl or alkyl groups other than methyl groups.  The systematic name of this enzyme class is '''geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase'''. This enzyme is also called '''(Z)-farnesyl diphosphate synthase'''.  

==References==
{{reflist|1}}
* {{cite journal | author = F, Bertini S, Brennan PJ, Crick DC | date = 2001 | title = Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis | journal = J. Biol. Chem.  | volume = 276 | pages = 11624&ndash;30  | pmid = 11152452 | doi = 10.1074/jbc.M007168200 | issue = 15 }}

{{transferase-stub}}

[[Category:EC 2.5.1]]
[[Category:Enzymes of unknown structure]]