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{{Infobox enzyme
| Name = Steroid-transporting ATPase
| EC_number = 3.6.3.45
| CAS_number = 
| IUBMB_EC_number = 3/6/3/45
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Steroid-transporting ATPase''' ({{EC number|3.6.3.45}}, ''pleiotropic-drug-resistance protein'', ''PDR protein'') is an [[enzyme]] with system name ''ATP phosphohydrolase (steroid-exporting)''.<ref>{{cite journal | title = Molecular cloning and characterization of a novel gene of ''Candida albicans'', CDR1, conferring multiple resistance to drugs and antifungals |author = Prasad, R., De Wergifosse, P., Goffeau, A. and Balzi, E. |journal = Curr. Genet. |year = 1995 |volume = 27 |pages = 320–329 |pmid = 7614555 |doi=10.1007/BF00352101}}</ref><ref>{{cite journal | title = ''bfr1<sup>+</sup>'', a novel gene of ''Schizosaccharomyces pombe'' which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily |author = Nagao, K., Taguchi, Y., Arioka, M., Kadokura, H., Takatsuki, A., Yoda, K. and Yamasaki, M. |journal = J. Bacteriol. |year = 1995 |volume = 177 |pages = 1536–1543 |pmid = 7883711 |pmc=176770 |issue=6}}</ref><ref>{{cite journal | title = The ATP-binding cassette transporters Pdr5 and Snq2 of ''Saccharomyces cerevisiae'' can mediate transport of steroids in vivo |author = Mah&eacute;, Y., Lemoine, Y. and Kuchler, K. |journal = J. Biol. Chem. |year = 1996 |volume = 271 |pages = 25167–25172 |pmid = 8810273 |doi=10.1074/jbc.271.41.25167}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: ATP + H<sub>2</sub>O + [[steroidin]] <math>\rightleftharpoons</math> ADP + [[phosphate]] + steroidout

This enzyme has two similar ATP-binding domains.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Steroid-transporting+ATPase}}

[[Category:EC 3.6.3]]