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{{enzyme
| Name = cadmium-exporting ATPase
| EC_number = 3.6.3.3
| CAS_number =
| IUBMB_EC_number = 3/6/3/3
| GO_code = 0008551
| image =
| width =
| caption =
}}
In [[enzymology]], a '''Cd2+-exporting ATPase''' ({{EC number|3.6.3.3}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:ATP + H2O + Cd2+in <math>\rightleftharpoons</math> ADP + phosphate + Cd2+out

The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]], [[water|H2O]], and [[Cadmium|Cd]]2+, whereas its 3 [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]], [[phosphate]], and [[Cadmium|Cd]]2+.

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is '''ATP phosphohydrolase (Cd2+-exporting)'''.

== Structural studies ==

As of late 2007, 4 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1MWY}}, {{PDB link|1MWZ}}, {{PDB link|2AJ0}}, and {{PDB link|2AJ1}}.

== References ==
{{reflist|1}}
* {{cite journal | author = Silver S, Ji G | year = 1994 | title = Newer systems for bacterial resistances to toxic heavy metals | journal = Environ. Health. Perspect. 102 Suppl | volume = 3 | pages = 107–13 | pmid = 7843081 | pmc = 1567394 }}
* {{cite journal | author = Tsai KJ, Linet AL | year = 1993 | title = Formation of a phosphorylated enzyme intermediate by the cadA Cd(2+)-ATPase | journal = Arch. Biochem. Biophys. | volume = 305 | pages = 267–70 | pmid = 8373163 | doi = 10.1006/abbi.1993.1421 | issue = 2 }}

[[Category:EC 3.6.3]]
[[Category:Enzymes of known structure]]

{{hydrolase-stub}}

Alpha-factor-transporting ATPase - Revision history

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