https://en.formulasearchengine.com/index.php?action=history&feed=atom&title=Complexification_%28Lie_group%29 Complexification (Lie group) - Revision history 2026-05-30T15:18:06Z Revision history for this page on the wiki MediaWiki 1.43.0-wmf.28 https://en.formulasearchengine.com/index.php?title=Complexification_(Lie_group)&diff=28972&oldid=prev 76.14.86.123 at 03:13, 26 July 2013 2013-07-26T03:13:32Z <p></p> <p><b>New page</b></p><div>{{Infobox enzyme<br /> | Name = Acyl-homoserine-lactone synthase<br /> | EC_number = 2.3.1.184<br /> | CAS_number = 176023-66-8<br /> | IUBMB_EC_number = 2/3/1/184<br /> | GO_code = <br /> | image = <br /> | width = <br /> | caption =<br /> }}<br /> &#039;&#039;&#039;Acyl-homoserine-lactone synthase&#039;&#039;&#039; ({{EC number|2.3.1.184}}, &#039;&#039;acyl-homoserine lactone synthase&#039;&#039;, &#039;&#039;acyl homoserine lactone synthase&#039;&#039;, &#039;&#039;acyl-homoserinelactone synthase&#039;&#039;, &#039;&#039;acylhomoserine lactone synthase&#039;&#039;, &#039;&#039;AHL synthase&#039;&#039;, &#039;&#039;AHS&#039;&#039;, &#039;&#039;AHSL synthase&#039;&#039;, &#039;&#039;AhyI&#039;&#039;, &#039;&#039;AinS&#039;&#039;, &#039;&#039;AinS protein&#039;&#039;, &#039;&#039;autoinducer synthase&#039;&#039;, &#039;&#039;autoinducer synthesis protein rhlI&#039;&#039;, &#039;&#039;EsaI&#039;&#039;, &#039;&#039;ExpISCC1&#039;&#039;, &#039;&#039;ExpISCC3065&#039;&#039;, &#039;&#039;LasI&#039;&#039;, &#039;&#039;LasR&#039;&#039;, &#039;&#039;LuxI&#039;&#039;, &#039;&#039;LuxI protein&#039;&#039;, &#039;&#039;LuxM&#039;&#039;, &#039;&#039;N-acyl homoserine lactone synthase&#039;&#039;, &#039;&#039;RhlI&#039;&#039;, &#039;&#039;YspI&#039;&#039;, &#039;&#039;acyl-[acyl carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)&#039;&#039;) is an [[enzyme]] with system name &#039;&#039;acyl-(acyl-carrier protein):S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)&#039;&#039;.&lt;ref&gt;{{cite journal | title = Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified &lt;em&gt;Vibrio fischeri&lt;/em&gt; LuxI protein |author = Schaefer, A.L., Val, D.L., Hanzelka, B.L., Cronan, J.E., Jr. and Greenberg, E.P. |journal = Proc. Natl. Acad. Sci. USA |year = 1996 |volume = 93 |pages = 9505–9509 |pmid = 8790360 |issue=18}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Crystallization and rhenium MAD phasing of the acyl-homoserinelactone synthase EsaI |author = Watson, W.T., Murphy, F.V., 4th, Gould, T.A., Jambeck, P., Val, D.L., Cronan, J.E., Jr., Beck von Bodman, S. and Churchill, M.E. |journal = Acta Crystallogr. D Biol. Crystallogr. |year = 2001 |volume = 57 |pages = 1945–1949 |pmid = 11717525 |issue=Pt 12}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Functional sites and evolutionary connections of acylhomoserine lactone synthases |author = Chakrabarti, S. and Sowdhamini, R. |journal = Protein Eng. |year = 2003 |volume = 16 |pages = 271–278 |pmid = 12736370 |issue=4}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Acylhomoserine lactone synthase activity of the &lt;em&gt;Vibrio fischeri&lt;/em&gt; AinS protein |author = Hanzelka, B.L., Parsek, M.R., Val, D.L., Dunlap, P.V., Cronan, J.E., Jr. and Greenberg, E.P. |journal = J. Bacteriol. |year = 1999 |volume = 181 |pages = 5766–5770 |pmid = 10482519 |issue=18}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Acyl homoserine-lactone quorum-sensing signal generation |author = Parsek, M.R., Val, D.L., Hanzelka, B.L., Cronan, J.E., Jr. and Greenberg, E.P. |journal = Proc. Natl. Acad. Sci. USA |year = 1999 |volume = 96 |pages = 4360–4365 |pmid = 10200267 |issue=8}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Quorum quenching: enzymatic disruption of &lt;em&gt;N&lt;/em&gt;-acylhomoserine lactone-mediated bacterial communication in &lt;em&gt;Burkholderia thailandensis&lt;/em&gt; |author = Ulrich, R.L. |journal = Appl. Environ. Microbiol. |year = 2004 |volume = 70 |pages = 6173–6180 |pmid = 15466564 |doi=10.1128/AEM.70.10.6173-6180.2004}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Structure of the &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; acyl-homoserinelactone synthase LasI |author = Gould, T.A., Schweizer, H.P. and Churchill, M.E. |journal = Mol. Microbiol. |year = 2004 |volume = 53 |pages = 1135–1146 |pmid = 15306017 |doi=10.1111/j.1365-2958.2004.04211.x |issue=4}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Chemical mechanism and substrate specificity of RhlI, an acylhomoserine lactone synthase from &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; |author = Raychaudhuri, A., Jerga, A. and Tipton, P.A. |journal = Biochemistry |year = 2005 |volume = 44 |pages = 2974–2981 |pmid = 15723540 |doi=10.1021/bi048005m |issue=8}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | title = Specificity of acyl-homoserine lactone synthases examined by mass spectrometry |author = Gould, T.A., Herman, J., Krank, J., Murphy, R.C. and Churchill, M.E. |journal = J. Bacteriol. |year = 2006 |volume = 188 |pages = 773–783 |pmid = 16385066 |doi=10.1128/JB.188.2.773-783.2006 |issue=2}}&lt;/ref&gt; This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]<br /> <br /> : acyl-[acyl-carrier protein] + [[S-adenosyl-L-methionine]] &lt;math&gt;\rightleftharpoons&lt;/math&gt; [acyl-carrier protein] + S-methyl-5&#039;-thioadenosine + N-acyl-L-homoserine lactone<br /> <br /> Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of [[virulence]] genes in a process known as [[quorum-sensing]].<br /> <br /> == References ==<br /> {{reflist}}<br /> <br /> == External links ==<br /> * {{MeshName|Acyl-homoserine-lactone+synthase}}<br /> <br /> [[Category:EC 2.3.1]]</div> 76.14.86.123