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gen fixes, added orphan tag, typos fixed: transfered → transferred using AWB

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{{Infobox enzyme
| Name = Sulfur carrier protein ThiS adenylyltransferase
| EC_number = 2.7.7.73
| CAS_number =
| IUBMB_EC_number = 2/7/7/73
| GO_code =
| image =
| width =
| caption =
}}
'''Sulfur carrier protein ThiS adenylyltransferase''' ({{EC number|2.7.7.73}}, ''thiF (gene)'') is an [[enzyme]] with system name ''ATP:(ThiS) adenylyltransferase''.<ref>{{cite journal | title = Thiamin biosynthesis in ''Escherichia coli''. Identification of this thiocarboxylate as the immediate sulfur donor in the thiazole formation |author = Taylor, S.V., Kelleher, N.L., Kinsland, C., Chiu, H.J., Costello, C.A., Backstrom, A.D., McLafferty, F.W. and Begley, T.P. |journal = J. Biol. Chem. |year = 1998 |volume = 273 |pages = 16555–16560 |pmid = 9632726 | doi = 10.1074/jbc.273.26.16555 | issue = 26}}</ref><ref>{{cite journal | title = Biosynthesis of the thiazole moiety of thiamin in ''Escherichia coli'': identification of an acyldisulfide-linked protein<sup>-</sup>-protein conjugate that is functionally analogous to the ubiquitin/E1 complex |author = Xi, J., Ge, Y., Kinsland, C., McLafferty, F.W. and Begley, T.P. |journal = Proc. Natl. Acad. Sci. USA |year = 2001 |volume = 98 |pages = 8513–8518 |pmid = 11438688 | doi = 10.1073/pnas.141226698 | issue = 15 | pmc = 37467}}</ref><ref>{{cite journal | title = Structural analysis of ''Escherichia coli'' ThiF |author = Duda, D.M., Walden, H., Sfondouris, J. and Schulman, B.A. |journal = J. Mol. Biol. |year = 2005 |volume = 349 |pages = 774–786 |pmid = 15896804 | doi = 10.1016/j.jmb.2005.04.011 | issue = 4}}</ref><ref>{{cite journal | title = Structure of the ''Escherichia coli'' ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis |author = Lehmann, C., Begley, T.P. and Ealick, S.E. |journal = Biochemistry |year = 2006 |volume = 45 |pages = 11–19 |pmid = 16388576 | doi = 10.1021/bi051502y | issue = 1 | pmc = 2566941}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: ATP + [ThiS] <math>\rightleftharpoons</math> [[diphosphate]] + adenylyl-[ThiS]

This enzyme binds Zn<sup>2+</sup>. The enzyme catalyses the [[adenylation]] of ThiS, a [[sulfur]] carrier protein involved in the [[biosynthesis]] of [[thiamine]].

== References ==
{{reflist}}

== External links ==
*{{MeshName|Sulfur+carrier+protein+ThiS+adenylyltransferase}}

[[Category:EC 2.7.7]]

Palinstrophy - Revision history

en>Download: gen fixes, added orphan tag, typos fixed: transfered → transferred using AWB