222.106.61.166: /* Pseudocode */

2013-10-22T13:11:34Z

Pseudocode

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{{Infobox enzyme
| Name = 23S rRNA (guanine2535-N1)-methyltransferase
| EC_number = 2.1.1.209
| CAS_number =
| IUBMB_EC_number = 2/1/1/209
| GO_code =
| image =
| width =
| caption =
}}
'''23S rRNA (guanine2535-N1)-methyltransferase''' ({{EC number|2.1.1.209}}, ''AviRa'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:23S rRNA (guanine2535-N1)-methyltransferase''.<ref>{{cite journal | title = The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose |author = Treede, I., Jakobsen, L., Kirpekar, F., Vester, B., Weitnauer, G., Bechthold, A. and Douthwaite, S. |journal = Mol. Microbiol. |year = 2003 |volume = 49 |pages = 309–318 |pmid = 12828631}}</ref><ref>{{cite journal | title = An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57 |author = Weitnauer, G., Gaisser, S., Trefzer, A., Stockert, S., Westrich, L., Quiros, L.M., Mendez, C., Salas, J.A. and Bechthold, A. |journal = Antimicrob. Agents Chemother. |year = 2001 |volume = 45 |pages = 690–695 |pmid = 11181344}}</ref><ref>{{cite journal | title = Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes |author = Mosbacher, T.G., Bechthold, A. and Schulz, G.E. |journal = J. Mol. Biol. |year = 2003 |volume = 329 |pages = 147–157 |pmid = 12742024}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[S-adenosyl-L-methionine]] + [[guanine]]2535 in [[23S ribosomal RNA|23S rRNA]] <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + N1-methylguanine2535 in 23S rRNA

This is one of the [[methyltransferase]]s from ''[[Streptomyces viridochromogenes]]'' .

== References ==
{{reflist}}

== External links ==
* {{MeshName|23S+rRNA+(guanine2535-N1)-methyltransferase}}

[[Category:EC 2.1.1]]

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222.106.61.166: /* Pseudocode */