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{{enzyme
| Name = Peroxisome-assembly ATPase
| EC_number = 3.6.4.7
| CAS_number =
| IUBMB_EC_number = 3/6/4/7
| GO_code =
| image =
| width =
| caption =
}}
In [[enzymology]], a '''peroxisome-assembly ATPase''' ({{EC number|3.6.4.7}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


:[[Adenosine triphosphate|ATP]] + [[Hydrogen|H]]<sub>2</sub>[[Oxygen|O]] <math>\rightleftharpoons</math> [[Adenosine diphosphate|ADP]] + [[phosphate]]


Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[phosphate]]. Its function is to transport components of the [[peroxisome]] in and out of the [[organelle]].
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This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on acid anhydrides to facilitate cellular and subcellular movement.  The systematic name of this enzyme class is '''ATP phosphohydrolase (peroxisome-assembling)'''. This enzyme is also called '''peroxisome assembly factor-2'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Lee YJ, Wickner RB | year = 1992 | title = AFG1, a new member of the SEC18-NSF, PAS1, CDC48-VCP, TBP family of ATPases | journal = Yeast. | volume = 8 | pages = 787&ndash;90  | pmid = 1441755 | doi = 10.1002/yea.320080912 | issue = 9 }}
* {{cite journal | author = T | year = 1995 | title = Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant | journal = Nat. Genet. | volume = 11 | pages = 395&ndash;401  | pmid = 7493019 | doi = 10.1038/ng1295-395 | issue = 4 | author-separator = , | author2 = Fujiki Y | author3 = Sakai F | author4 = Bogaki A | display-authors = 4 | last5 = Shimozawa | first5 = Nobuyuki | last6 = Suzuki | first6 = Yasuyuki | last7 = Orii | first7 = Tadao | last8 = Fujiki | first8 = Yukio | last9 = Sakai | first9 = Fumie }}
* {{cite journal | author = Valle D, Gould SJ | year = 1996 | title = The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor | journal = EMBO J.  | volume = 15 | pages = 2914&ndash;23  | pmid = 8670792 | issue = 12 | pmc = 450231 }}
 
[[Category:EC 3.6.4]]
[[Category:Enzymes of unknown structure]]
 
 
{{hydrolase-stub}}

Latest revision as of 21:25, 5 June 2014


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