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| == Nike Blazers High == | | {{enzyme |
| | | Name = 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
| | | EC_number = 1.1.1.178 |
| | | CAS_number = 52227-66-4 |
| | | IUBMB_EC_number = 1/1/1/178 |
| | | GO_code = 0047015 |
| | | image = |
| | | width = |
| | | caption = |
| | }} |
| | In [[enzymology]], a '''3-hydroxy-2-methylbutyryl-CoA dehydrogenase''' ({{EC number|1.1.1.178}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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| | :(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD<sup>+</sup> <math>\rightleftharpoons</math> 2-methylacetoacetyl-CoA + NADH + H<sup>+</sup> |
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| | This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD<sup>+</sup> oxidoreductase'''. Other names in common use include '''2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase''', '''2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase''', and '''2-methyl-3-hydroxy-butyryl CoA dehydrogenase'''. This enzyme participates in [[valine, leucine and isoleucine degradation]]. |
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Template:Enzyme
In enzymology, a 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction
- (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD+ 2-methylacetoacetyl-CoA + NADH + H+
Thus, the two substrates of this enzyme are (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA and NAD+, whereas its 3 products are 2-methylacetoacetyl-CoA, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase. Other names in common use include 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, and 2-methyl-3-hydroxy-butyryl CoA dehydrogenase. This enzyme participates in valine, leucine and isoleucine degradation.
Structural studies
As of 20 January 2010, 6 structure have been solved for this class of enzymes, with the PDB accession code Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link.
References
43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.
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