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| The '''Reid Index''' is a mathematical relationship that exists in a human [[bronchus]] section observed under the [[microscope]]. It is defined as ratio between the thickness of the submucosal [[mucus]] secreting [[gland]]s and the thickness between the [[epithelium]] and [[cartilage]] that covers the [[Bronchus|bronchi]]. The Reid index is not of diagnostic use ''in vivo'' since it requires a dissection of the airway tube, but it has value in ''post mortem'' evaluations and for research.<ref>B. Karger, T. Fracasso, B. Brinkmann and T. Bajanowski. ''Evaluation of the Reid index in infants and cases of SIDS''. International Journal of Legal Medicine. Volume 118, Number 4 / August, 2004. [http://www.springerlink.com/content/5eey33q9ul81n8h6/]</ref>
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| ==Calculation==
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| :<math>\ RI = \frac {gland}{wall}</math>
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| where:
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| : '''RI''' is the Reid Index
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| :''wall'' is the thickness of the airway wall between the [[epithelium]] and the [[cartilage]]'s [[perichondrium]]
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| :''gland'' is the thickness of the mucous producing gland at the location of inspection.
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| ==Interpretation==
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| A normal Reid Index should be smaller than 0.4, the thickness of the wall is always more than double the thickness of the glands it contains. A greater value is the most pathognomonic indicator of chronic bronchitis.
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| [[Hyperplasia]] and [[hypertrophy]] of mucous glands as in [[chronic bronchitis]]<ref>[http://www.som.tulane.edu/classware/pathology/medical_pathology/New_for_98/Lung_Review/Lung-20.html School of Medicine, Tulane University]</ref> causes them to be present at deeper levels in the bronchial wall and thicker in size, thus increasing the Reid Index beyond the normal value.
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| ==References==
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| {{reflist|2}}
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| {{Eponymous medical signs for respiratory system}}
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| [[Category:Respiratory system]]
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Latest revision as of 10:52, 19 May 2014
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