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| {{enzyme
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| | Name = L-idonate 2-dehydrogenase
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| | EC_number = 1.1.1.128
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| | CAS_number = 37250-57-0
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| | IUBMB_EC_number = 1/1/1/128
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| | GO_code = 0050027
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| In [[enzymology]], a '''L-idonate 2-dehydrogenase''' ({{EC number|1.1.1.128}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :L-idonate + NADP<sup>+</sup> <math>\rightleftharpoons</math> 5-dehydro-D-gluconate + NADPH + H<sup>+</sup>
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-idonate]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[5-dehydro-D-gluconate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''L-idonate:NADP<sup>+</sup> 2-oxidoreductase'''. Other names in common use include '''5-ketogluconate 2-reductase''', '''5-keto-D-gluconate 2-reductase''', '''L-idonate dehydrogenase''', '''5-ketogluconate 2-reductase''', '''reductase, 5-ketogluconate 5- (L-idonate-forming)''', '''5KGR''', and '''5-ketoglucono-idono-reductase'''.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Takagi Y | date = 1962 | title = A new enzyme, 5-ketoglucono-idono-reductase | journal = Agric. Biol. Chem. | volume = 26 | pages = 719–720 }}
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| [[Category:EC 1.1.1]]
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| [[Category:NADPH-dependent enzymes]]
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| [[Category:Enzymes of unknown structure]]
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| {{1.1.1-enzyme-stub}}
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Latest revision as of 12:41, 26 May 2014
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