3,4-dihydroxyphenylacetate 2,3-dioxygenase: Difference between revisions

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{{enzyme
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| Name = Acetylacetone-cleaving enzyme
| EC_number = 1.13.11.50
| CAS_number = 524047-53-8
| IUBMB_EC_number = 1/13/11/50
| GO_code =
| image =
| width =
| caption =
}}
In [[enzymology]], an '''acetylacetone-cleaving enzyme''' ({{EC number|1.13.11.50}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


:pentane-2,4-dione + O<sub>2</sub> <math>\rightleftharpoons</math> acetate + 2-oxopropanal
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[pentane-2,4-dione]] and [[oxygen|O<sub>2</sub>]], whereas its two [[product (chemistry)|products]] are [[acetate]] and [[2-oxopropanal]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O<sub>2</sub>. The systematic name of this enzyme class is '''acetylacetone:oxygen oxidoreductase'''. Other names in common use include '''Dke1''', '''acetylacetone dioxygenase''', '''diketone cleaving dioxygenase''', and '''diketone cleaving enzyme'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Straganz GD, Glieder A, Brecker L, Ribbons DW, Steiner W | date = 2003 | title = Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii | journal = Biochem. J. | volume = 369 | pages = 573&ndash;81  | pmid = 12379146 | doi = 10.1042/BJ20021047 | issue = Pt 3 | pmc = 1223103 }}
 
[[Category:EC 1.13.11]]
[[Category:Enzymes of unknown structure]]

Revision as of 17:21, 3 March 2014

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