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{{enzyme
| Name = UDP-glucuronate 5'-epimerase
| EC_number = 5.1.3.12
| CAS_number = 37318-38-0
| IUBMB_EC_number = 5/1/3/12
| GO_code = 0050379
| image =
| width =
| caption =
}}
In [[enzymology]], an '''UDP-glucuronate 5'-epimerase''' ({{EC number|5.1.3.12}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:UDP-glucuronate <math>\rightleftharpoons</math> UDP-L-iduronate
 
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[UDP-glucuronate]], and one [[product (chemistry)|product]], [[UDP-L-iduronate]].
 
This enzyme belongs to the family of [[isomerase]]s, specifically those [[racemase]]s and [[epimerase]]s acting on [[carbohydrate]]s and derivatives. The systematic name of this enzyme class is '''UDP-glucuronate 5'-epimerase'''. Other names in common use include '''uridine diphosphoglucuronate 5'-epimerase''', '''UDP-glucuronic acid 5'-epimerase''', and '''C-5-uronosyl epimerase'''. This enzyme participates in [[nucleotide sugars metabolism]]. It employs one [[cofactor (biochemistry)|cofactor]], [[NAD+]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Jacobson B and Davidson EA | date = 1962 | title = Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5-epimerase | journal = J. Biol. Chem. | volume = 237 | pages = 638&ndash;642 | pmid=14450717}}
 
{{isomerase-stub}}
 
[[Category:EC 5.1.3]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 09:30, 20 July 2013

Template:Enzyme In enzymology, an UDP-glucuronate 5'-epimerase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate UDP-L-iduronate

Hence, this enzyme has one substrate, UDP-glucuronate, and one product, UDP-L-iduronate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-glucuronate 5'-epimerase. Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl epimerase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, NAD+.

References

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Template:Isomerase-stub