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{{enzyme
| Name = phosphoadenylylsulfatase
| EC_number = 3.6.2.2
| CAS_number = 37289-37-5
| IUBMB_EC_number = 3/6/2/2
| GO_code = 0050186
| image =
| width =
| caption =
}}
In [[enzymology]], a '''phosphoadenylylsulfatase''' ({{EC number|3.6.2.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:3'-phosphoadenylyl sulfate + H<sub>2</sub>O <math>\rightleftharpoons</math> adenosine 3',5'-bisphosphate + sulfate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[sulfate]].
 
This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on acid anhydrides in sulfonyl-containing anhydrides. The systematic name of this enzyme class is '''3'-phosphoadenylyl-sulfate sulfohydrolase'''. Other names in common use include '''3-phosphoadenylyl sulfatase''', '''3-phosphoadenosine 5-phosphosulfate sulfatase''', '''PAPS sulfatase''', and '''3'-phosphoadenylylsulfate sulfohydrolase'''This enzyme participates in [[sulfur metabolism]]. It employs one [[cofactor (biochemistry)|cofactor]], [[manganese]].
 
==References==
{{reflist|1}}
* {{cite journal | author = BALASUBRAMANIAN AS, BACHHAWAT BK | date = 1962 | title = Enzymic degradation of active sulphate | journal = Biochim. Biophys. Acta. | volume = 59 | issue = 2 | pages = 389&ndash;97  | pmid = 13864264 | doi = 10.1016/0006-3002(62)90188-9 }}
 
{{hydrolase-stub}}
{{Acid anhydride hydrolases}}
[[Category:EC 3.6.2]]
[[Category:Manganese enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 23:54, 8 February 2013

Template:Enzyme In enzymology, a phosphoadenylylsulfatase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + H2O adenosine 3',5'-bisphosphate + sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and H2O, whereas its two products are adenosine 3',5'-bisphosphate and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in sulfonyl-containing anhydrides. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate sulfohydrolase. Other names in common use include 3-phosphoadenylyl sulfatase, 3-phosphoadenosine 5-phosphosulfate sulfatase, PAPS sulfatase, and 3'-phosphoadenylylsulfate sulfohydrolase. This enzyme participates in sulfur metabolism. It employs one cofactor, manganese.

References

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Template:Hydrolase-stub Template:Acid anhydride hydrolases