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{{enzyme
| Name = tabersonine 16-hydroxylase
| EC_number = 1.14.13.73
| CAS_number = 250378-34-8
| IUBMB_EC_number = 1/14/13/73
| GO_code = 0050594
| image =  
| width =  
| caption =  
}}
In [[enzymology]], a '''tabersonine 16-hydroxylase''' ({{EC number|1.14.13.73}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:tabersonine + NADPH + H<sup>+</sup> + O<sub>2</sub> <math>\rightleftharpoons</math> 16-hydroxytabersonine + NADP<sup>+</sup> + H<sub>2</sub>O
 
The 4 [[substrate (biochemistry)|substrates]] of this enzyme are [[tabersonine]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], [[hydrogen ion|H<sup>+</sup>]], and [[oxygen|O<sub>2</sub>]], whereas its 3 [[product (chemistry)|products]] are [[16-hydroxytabersonine]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is '''tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)'''. Other names in common use include '''tabersonine-11-hydroxylase''', and '''T11H'''This enzyme participates in [[indole and ipecac alkaloid biosynthesis]].
 
==References==
{{reflist|1}}
* {{cite journal | author = St-Pierre B, De Luca V | date = 1995 | title = A Cytochrome P-450 Monooxygenase Catalyzes the First Step in the Conversion of Tabersonine to Vindoline in Catharanthus roseus | journal = Plant. Physiol. | volume = 109 | pages = 131&ndash;139  | pmid = 12228585 | issue = 1 | pmc = 157569 }}
 
{{1.14.13-enzyme-stub}}
 
[[Category:EC 1.14.13]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 03:46, 2 March 2013

Template:Enzyme In enzymology, a tabersonine 16-hydroxylase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

tabersonine + NADPH + H+ + O2 16-hydroxytabersonine + NADP+ + H2O

The 4 substrates of this enzyme are tabersonine, NADPH, H+, and O2, whereas its 3 products are 16-hydroxytabersonine, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating). Other names in common use include tabersonine-11-hydroxylase, and T11H. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

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Template:1.14.13-enzyme-stub