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{{enzyme
| Name = Aldehyde dehydrogenase (FAD-independent)
| EC_number = 1.2.99.7
| CAS_number =
| IUBMB_EC_number = 1/2/99/7
| GO_code =
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aldehyde dehydrogenase (FAD-independent)''' ({{EC number|1.2.99.7}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:an aldehyde + H<sub>2</sub>O + acceptor <math>\rightleftharpoons</math> a carboxylate + reduced acceptor
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[aldehyde]], [[water|H<sub>2</sub>O]], and [[Electron acceptor|acceptor]], whereas its two [[product (chemistry)|products]] are [[carboxylate]] and [[reduced acceptor]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the aldehyde or oxo group of donor with other acceptors.  The systematic name of this enzyme class is '''aldehyde:acceptor oxidoreductase (FAD-independent)'''. Other names in common use include '''aldehyde oxidase''', '''aldehyde oxidoreductase''', '''Mop''', and '''AORDd'''.   
 
==Structural studies==
 
As of late 2007, only one [[tertiary structure|structure]] has been solved for this class of enzymes, with the [[Protein Data Bank|PDB]] accession code {{PDB link|1ZCS}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = Fujishiro K, Aisaka K, Uwajima T | date = 2003 | title = Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690 | journal = FEMS. Microbiol. Lett. | volume = 229 | pages = 31&ndash;6  | pmid = 14659539 | doi = 10.1016/S0378-1097(03)00781-X | issue = 1 }}
* {{cite journal | author = MJ, Moura JJ | date = 2000 | title = Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774 | journal = Biochem. Biophys. Res. Commun| volume = 268 | pages = 745&ndash;9  | pmid = 10679276 | doi = 10.1006/bbrc.2000.2135 | last2 = Archer | first2 = M | last3 = Dias | first3 = JM | last4 = Bursakov | first4 = S | last5 = Huber | first5 = R | last6 = Moura | first6 = I | last7 = Romão | first7 = MJ | last8 = Moura | first8 = JJ | issue = 3 }}
* {{cite journal | author = Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ | date = 2000 | title = Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site | journal = Eur. J. Biochem.  | volume = 267 | pages = 2054&ndash;61  | pmid = 10727945 | doi = 10.1046/j.1432-1327.2000.01209.x | issue = 7 }}
* {{cite journal | author = M, Hof P, Huber R | date = 1995 | title = Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas | journal = Science. | volume = 270 | pages = 1170&ndash;6  | pmid = 7502041 | doi = 10.1126/science.270.5239.1170 | issue = 5239 }}
 
{{1.2-enzyme-stub}}
 
[[Category:EC 1.2.99]]
[[Category:Enzymes of known structure]]

Latest revision as of 03:54, 2 March 2013

Template:Enzyme In enzymology, an aldehyde dehydrogenase (FAD-independent) (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

an aldehyde + H2O + acceptor a carboxylate + reduced acceptor

The 3 substrates of this enzyme are aldehyde, H2O, and acceptor, whereas its two products are carboxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with other acceptors. The systematic name of this enzyme class is aldehyde:acceptor oxidoreductase (FAD-independent). Other names in common use include aldehyde oxidase, aldehyde oxidoreductase, Mop, and AORDd.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

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Template:1.2-enzyme-stub