Abscisic-aldehyde oxidase: Difference between revisions

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{{enzyme
| Name = aminomuconate-semialdehyde dehydrogenase
| EC_number = 1.2.1.32
| CAS_number = 37250-95-6
| IUBMB_EC_number = 1/2/1/32
| GO_code = 0047102
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aminomuconate-semialdehyde dehydrogenase''' ({{EC number|1.2.1.32}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:2-aminomuconate 6-semialdehyde + NAD<sup>+</sup> + H<sub>2</sub>O <math>\rightleftharpoons</math> 2-aminomuconate + NADH + 2 H<sup>+</sup>
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[2-aminomuconate 6-semialdehyde]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[2-aminomuconate]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H<sup>+</sup>]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is '''2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase'''. Other names in common use include '''2-aminomuconate semialdehyde dehydrogenase''', '''2-hydroxymuconic acid semialdehyde dehydrogenase''', '''2-hydroxymuconate semialdehyde dehydrogenase''', '''alpha-aminomuconic epsilon-semialdehyde dehydrogenase''', '''alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase''', and '''2-hydroxymuconic semialdehyde dehydrogenase'''This enzyme participates in 3 [[metabolism|metabolic pathways]]: [[benzoic acid]] degradation via [[hydroxylation]], [[tryptophan]] metabolism, and the degradation pathway for [[toluene]] and [[xylene]]. 
 
==References==
{{reflist|1}}
* {{cite journal | author = SENOH S | date = 1965 | title = STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID | journal = J. Biol. Chem. | volume = 240 | pages = 740&ndash;9  | pmid = 14275130 | last2 = Nakamura | first2 = S | last3 = Kawai | first3 = H | last4 = Honjo | first4 = T | last5 = Nishizuka | first5 = Y | last6 = Hayaishi | first6 = O | last7 = Senoh | first7 = S }}
 
{{1.2-enzyme-stub}}
{{Amino acid metabolism enzymes}}
[[Category:EC 1.2.1]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 18:37, 23 June 2013

Template:Enzyme In enzymology, an aminomuconate-semialdehyde dehydrogenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

2-aminomuconate 6-semialdehyde + NAD+ + H2O 2-aminomuconate + NADH + 2 H+

The 3 substrates of this enzyme are 2-aminomuconate 6-semialdehyde, NAD+, and H2O, whereas its 3 products are 2-aminomuconate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase. Other names in common use include 2-aminomuconate semialdehyde dehydrogenase, 2-hydroxymuconic acid semialdehyde dehydrogenase, 2-hydroxymuconate semialdehyde dehydrogenase, alpha-aminomuconic epsilon-semialdehyde dehydrogenase, alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase, and 2-hydroxymuconic semialdehyde dehydrogenase. This enzyme participates in 3 metabolic pathways: benzoic acid degradation via hydroxylation, tryptophan metabolism, and the degradation pathway for toluene and xylene.

References

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Template:1.2-enzyme-stub Template:Amino acid metabolism enzymes