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{{enzyme
| Name = dihydroxyphenylalanine ammonia-lyase
| EC_number = 4.3.1.11
| CAS_number = 37290-92-9
| IUBMB_EC_number = 4/3/1/11
| GO_code = 0047859
| image =
| width =
| caption =
}}
In [[enzymology]], a '''dihydroxyphenylalanine ammonia-lyase''' ({{EC number|4.3.1.11}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:3,4-dihydroxy-L-phenylalanine <math>\rightleftharpoons</math> trans-caffeate + NH<sub>3</sub>
 
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[3,4-dihydroxy-L-phenylalanine]] (L-DOPA), and two [[product (chemistry)|products]], [[trans-caffeate]] and [[ammonia|NH<sub>3</sub>]].
 
This enzyme belongs to the family of [[lyase]]s, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is '''3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming)'''. Other names in common use include '''beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase''', and '''3,4-dihydroxy-L-phenylalanine ammonia-lyase'''. This enzyme participates in [[tyrosine metabolism]]. 
 
== References ==
{{reflist|1}}
* {{cite journal | author = MacLeod NJ and Pridham JB | date = 1963 | title = Deamination of beta-(3,4-dihydroxyphenyl)-L-alanine by plants | journal = Biochem. J. | volume = 88 | pages = 45 | pmid = 16749027 | issue = 1 | pmc = 1203845 }}
 
{{lyase-stub}}
 
[[Category:EC 4.3.1]]
[[Category:Enzymes of unknown structure]]
[[Category:Hydroxycinnamic acids metabolism]]

Revision as of 20:09, 17 March 2013

Template:Enzyme In enzymology, a dihydroxyphenylalanine ammonia-lyase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

3,4-dihydroxy-L-phenylalanine trans-caffeate + NH3

Hence, this enzyme has one substrate, 3,4-dihydroxy-L-phenylalanine (L-DOPA), and two products, trans-caffeate and NH3.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming). Other names in common use include beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase, and 3,4-dihydroxy-L-phenylalanine ammonia-lyase. This enzyme participates in tyrosine metabolism.

References

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