Haloacetate dehalogenase

Template:Enzyme In enzymology, a phosphonoacetate hydrolase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

phosphonoacetate + H₂O $\rightleftharpoons$ acetate + phosphate

Thus, the two substrates of this enzyme are phosphonoacetate and H₂O, whereas its two products are acetate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-phosphorus bonds. The systematic name of this enzyme class is phosphonoacetate phosphonohydrolase. This enzyme participates in aminophosphonate metabolism. It employs one cofactor, zinc.

Structural studies

The structure of this enzyme, with the PDB accession code Template:PDB link, shows it adopts the alkaline phosphatase fold.

References

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