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{{enzyme
| Name = branched-chain-2-oxoacid decarboxylase
| EC_number = 4.1.1.72
| CAS_number = 63653-19-0
| IUBMB_EC_number = 4/1/1/72
| GO_code = 0047433
| image =
| width =
| caption =
}}
In [[enzymology]], a '''branched-chain-2-oxoacid decarboxylase''' ({{EC number|4.1.1.72}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:(3S)-3-methyl-2-oxopentanoate <math>\rightleftharpoons</math> 2-methylbutanal + CO<sub>2</sub>
 
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[(3S)-3-methyl-2-oxopentanoate]], and two [[product (chemistry)|products]], [[2-methylbutanal]] and [[carbon dioxide|CO<sub>2</sub>]].
 
This enzyme belongs to the family of [[lyase]]s, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is '''(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)'''. Other names in common use include '''branched-chain oxo acid decarboxylase''', '''branched-chain alpha-keto acid decarboxylase''', '''branched-chain keto acid decarboxylase''', '''BCKA''', and '''(3S)-3-methyl-2-oxopentanoate carboxy-lyase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Oku H, Kaneda T | date = 1988 | title = Biosynthesis of branched-chain fatty acids in Bacillus subtilis. A decarboxylase is essential for branched-chain fatty acid synthetase | journal = J. Biol. Chem. | volume = 263 | pages = 18386&ndash;96  | pmid = 3142877 | issue = 34 }}
 
{{4.1-enzyme-stub}}
 
[[Category:EC 4.1.1]]
[[Category:Enzymes of unknown structure]]

Revision as of 19:14, 9 November 2013

Template:Enzyme In enzymology, a branched-chain-2-oxoacid decarboxylase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

(3S)-3-methyl-2-oxopentanoate 2-methylbutanal + CO2

Hence, this enzyme has one substrate, (3S)-3-methyl-2-oxopentanoate, and two products, 2-methylbutanal and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming). Other names in common use include branched-chain oxo acid decarboxylase, branched-chain alpha-keto acid decarboxylase, branched-chain keto acid decarboxylase, BCKA, and (3S)-3-methyl-2-oxopentanoate carboxy-lyase.

References

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