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{{enzyme
| Name = glucarate dehydratase
| EC_number = 4.2.1.40
| CAS_number = 9059-02-3
| IUBMB_EC_number = 4/2/1/40
| GO_code = 0008872
| image =
| width =
| caption =
}}
In [[enzymology]], a '''glucarate dehydratase''' ({{EC number|4.2.1.40}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:D-glucarate <math>\rightleftharpoons</math> 5-dehydro-4-deoxy-D-glucarate + H<sub>2</sub>O
 
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[D-glucarate]], and two [[product (chemistry)|products]], [[5-dehydro-4-deoxy-D-glucarate]] and [[water|H<sub>2</sub>O]].
 
This enzyme belongs to the family of [[lyase]]s, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is '''D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)'''. Other names in common use include '''D-glucarate dehydratase''', and '''D-glucarate hydro-lyase'''.  This enzyme participates in [[ascorbate and aldarate metabolism]].
 
==Structural studies==
 
As of late 2007, 7 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1BQG}}, {{PDB link|1EC7}}, {{PDB link|1EC8}}, {{PDB link|1EC9}}, {{PDB link|1ECQ}}, {{PDB link|1JCT}}, and {{PDB link|1JDF}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = Blumenthal HJ | date = 1966 | title = D-Glucarate dehydrase | journal = Methods Enzymol. | volume = 9 | pages = 660&ndash;665 }}
 
{{4.2-enzyme-stub}}
 
[[Category:EC 4.2.1]]
[[Category:Enzymes of known structure]]

Latest revision as of 00:22, 26 May 2013

Template:Enzyme In enzymology, a glucarate dehydratase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

D-glucarate 5-dehydro-4-deoxy-D-glucarate + H2O

Hence, this enzyme has one substrate, D-glucarate, and two products, 5-dehydro-4-deoxy-D-glucarate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming). Other names in common use include D-glucarate dehydratase, and D-glucarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.

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Template:4.2-enzyme-stub