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{{enzyme
| Name = inositol 3-kinase
| EC_number = 2.7.1.64
| CAS_number = 37278-07-2
| IUBMB_EC_number = 2/7/1/64
| GO_code = 0019140
| image =
| width =
| caption =
}}
In [[enzymology]], an '''inositol 3-kinase''' ({{EC number|2.7.1.64}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:ATP + myo-inositol <math>\rightleftharpoons</math> ADP + 1D-myo-inositol 3-phosphate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[myo-inositol]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[1D-myo-inositol 3-phosphate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with an alcohol group as acceptor. The systematic name of this enzyme class is '''ATP:myo-inositol 1-phosphotransferase'''. Other names in common use include '''inositol-1-kinase (phosphorylating)''', '''myoinositol kinase''', and '''myo-inositol 1-kinase'''.  This enzyme participates in [[inositol phosphate metabolism]].
 
==References==
{{reflist|1}}
* {{cite journal | author = English PD, Dietz M and Albersheim P | date = 1966 | title = Myoinositol kinase: partial purification and identification of product | journal = Science  | volume = 151 | issue = 3707 | pages = 198&ndash;199 | doi = 10.1126/science.151.3707.198 }}
* {{cite journal | author = and Loewus FA | date = 1982 | title = Enantiomeric form of myo-inositol-1-phosphate produced by myo-inositol-1-phosphate synthase and myoinositol kinase in higher-plants | journal = Plant Physiol| volume = 70 | issue = 6 | pages = 1661&ndash;1663 | doi = 10.1104/pp.70.6.1661 | last2 = Sasaki | first2 = K. | last3 = Leavitt | first3 = A. L. | last4 = Munsell | first4 = L. | last5 = Sherman | first5 = W. R. | last6 = Loewus | first6 = F. A. }}
* {{cite journal | author = Stephens LR, Kay RR, Irvine RF | date = 1990 | title = A myo-inositol D-3 hydroxykinase activity in Dictyostelium | journal = Biochem. J. | volume = 272 | pages = 201&ndash;10  | pmid = 2176081 | issue = 1 | pmc = 1149677 }}
 
{{enzyme-stub}}
 
[[Category:EC 2.7.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 04:16, 21 January 2014

Template:Enzyme In enzymology, an inositol 3-kinase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

ATP + myo-inositol ADP + 1D-myo-inositol 3-phosphate

Thus, the two substrates of this enzyme are ATP and myo-inositol, whereas its two products are ADP and 1D-myo-inositol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:myo-inositol 1-phosphotransferase. Other names in common use include inositol-1-kinase (phosphorylating), myoinositol kinase, and myo-inositol 1-kinase. This enzyme participates in inositol phosphate metabolism.

References

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