2-dehydro-3-deoxy-L-pentonate aldolase: Difference between revisions

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{{enzyme
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| Name = 3-hydroxy-3-isohexenylglutaryl-CoA lyase
| EC_number = 4.1.3.26
| CAS_number = 37290-69-0
| IUBMB_EC_number = 4/1/3/26
| GO_code = 0047445
| image =
| width =
| caption =
}}
In [[enzymology]], a '''3-hydroxy-3-isohexenylglutaryl-CoA lyase''' ({{EC number|4.1.3.26}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <math>\rightleftharpoons</math> 7-methyl-3-oxooct-6-enoyl-CoA + acetate
 
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA]], and two [[product (chemistry)|products]], [[7-methyl-3-oxooct-6-enoyl-CoA]] and [[acetate]].
 
This enzyme belongs to the family of [[lyase]]s, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is '''3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)'''. Other names in common use include '''beta-hydroxy-beta-isohexenylglutaryl CoA-lyase''', '''hydroxyisohexenylglutaryl-CoA:acetatelyase''', '''3-hydroxy-3-isohexenylglutaryl coenzyme A lyase''', '''3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase''', and '''3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = SEUBERT W, FASS E | date = 1964 | title = [STUDIES ON THE BACTERIAL DEGRADATION OF ISOPRENOIDS. IV. THE PURIFICATION AND PROPERTIES OF BETA-ISOHEXENYLGLUTACONYL-COA-HYDRATASE AND BETA-HYDROXY-BETA-ISOHEXENYLGLUTARYL-COA-LYASE.] | journal = Biochem. Z.  | volume = 341 | pages = 23&ndash;34  | pmid = 14339651 }}
 
{{4.1-enzyme-stub}}
 
[[Category:EC 4.1.3]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 07:32, 17 May 2014

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