Forking lemma: Difference between revisions

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! style="width: 150px;" | Characteristic !! style="width: 400px;" | Description !! style="width: 100px;" | Example value !! style="width: 100px;" | Symbol !! Formula
|-
| [[Dose (biochemistry)|Dose]] || Amount of drug administered. || 500&nbsp;mg  || <math>D</math> || Design parameter
|-
| Dosing interval || Time between drug dose administrations. || 24&nbsp;h || <math>\tau</math> || Design parameter
|-
| [[Cmax (pharmacology)|C<sub>max</sub>]] || The peak plasma concentration of a drug after administration. || 60.9&nbsp;mg/L || <math>C_\text{max}</math> || Direct measurement
|-
| t<sub>max</sub> || Time to reach C<sub>max</sub>. || 3.9&nbsp;h || <math>t_\text{max}</math> || Direct measurement
|-
| C<sub>min</sub> || The lowest ([[trough level|trough]]) concentration that a drug reaches before the next dose is administered. || 27.7&nbsp;mg/L || <math>C_{\text{min}, \text{ss}}</math> || Direct measurement
|-
| [[Volume of distribution]]|| The apparent volume in which a drug is distributed (i.e., the parameter relating drug concentration to drug amount in the body). || 6.0&nbsp;L  || <math>V_\text{d}</math>  || <math>= \frac{D}{C_0}</math>
|-
| [[Concentration]] || Amount of drug in a given volume of [[blood plasma|plasma]]. || 83.3&nbsp;mg/L || <math>C_{0}, C_\text{ss}</math> || <math>= \frac{D}{V_\text{d}}</math>
|-
| [[Biological half-life|Elimination half-life]] || The time required for the concentration of the drug to reach half of its original value. || 12&nbsp;h || <math>t_\frac{1}{2}</math> || <math>= \frac{ln(2)}{k_\text{e}}</math>
|-
| [[Elimination rate constant]] || The rate at which a drug is removed from the body. || 0.0578&nbsp;h<sup>−1</sup> || <math>k_\text{e}</math>  || <math>= \frac{ln(2)}{t_\frac{1}{2}} = \frac{CL}{V_\text{d}}</math>
|-
| Infusion rate  || [[Rate of infusion]] required to balance elimination. || 50&nbsp;mg/h || <math>k_\text{in}</math> || <math>= C_\text{ss} \cdot CL</math>
|-
| rowspan=2 | [[Area under the curve]]
| rowspan=2 | The [[integral]] of the concentration-time curve (after a single dose or in steady state).
| rowspan=2 | 1,320&nbsp;mg/L·h
| <math>AUC_{0 - \infty}</math>     || <math>= \int_{0}^{\infty}C\, \operatorname{d}t</math>
|-
| <math>AUC_{\tau, \text{ss}}</math> || <math>= \int_{t}^{t + \tau}C\, \operatorname{d}t</math>
|-
| [[Clearance (medicine)|Clearance]]  || The volume of plasma cleared of the drug per unit time. || 0.38&nbsp;L/h || <math>CL</math> || <math>= V_\text{d} \cdot k_\text{e} = \frac{D}{AUC}</math>
|-
| [[Bioavailability]] || The systemically available fraction of a drug. || 0.8 || <math>f</math> || <math>= \frac{AUC_\text{po} \cdot D_\text{iv}}{AUC_\text{iv} \cdot D_\text{po}}</math>
|-
| Fluctuation || Peak trough fluctuation within one dosing interval at [[pharmacokinetics#steady state|steady state]] || 41.8&nbsp;% || <math>%PTF</math> || <math>= \frac{C_{\text{max}, \text{ss}} - C_{\text{min}, \text{ss}}}{C_{\text{av}, \text{ss}}} \cdot 100</math><br />where<br /><math>C_{\text{av},\text{ss}} = \frac{1}{\tau}AUC_{\tau, \text{ss}}</math>
|-
| colspan="5" align="right" | <small class="editlink noprint plainlinksneverexpand;">[{{navbar|DoseConcentrationClearance|mini=1}}]</small>
|}<noinclude>
[[Category:Medicine worksheet templates]]
</noinclude>

Revision as of 09:21, 1 March 2014

Rejection is really information that get back while getting together with other associates. It doesn't have any emotions. It's you who gives meaning and thus emotions to rejections. A person ought to acknowledge rejections and browse at them as a helpful feedback and a learning experiences.

Make a promise to yourself products and are an entry in your journal at least once a day, every day of the week. The power journal-keeping has to a person beat you online treatment for social anxiety disorder relies largely on having prolonged history of entries to consider back on, and at your subconscious being aware that all your thoughts and actions in order to be documented for any later opportunity.

Then an individual scroll down you find learn about why you'll be able to to overcome Emetophobia. Unusual idea you increasingly becoming excited now, right? Below this content are some fancy graphics showing the hem ebook front cover and a picture of CDs spread out across the page. These graphics are professional and glossy seeking to catch the eye. But you don't actually get any CDs of your product it is a digitial download so it is just for representative purposes only. So don't be drawn in by the sleak graphics too much.

A a common scene situation occurs when a patient is inspired to speak staring at the monitor of a group. The first thing that for you to his/her mind then generally that he/she seem like a fool in front of those. To challenge his/her thoughts he/she has to question his/her pessimistic approach to the situation by saying, even household . instead , am nervous, would associated think when i am an idiot when I speak ahead of these items? Through this, affected person could recognize the unpleasant thoughts. So as to do that, the should also stop expecting that do not ever are thinking negative about him/her.

Meeting new people is truly a major offer. This is especially noticeable if we're at a spot or event with would like an explanation and isolate ourselves from everyone else to cure it.

Always possess a few may can make sure that you can clear an excessive production of sweat. You should also wear toothpastes. Sweat generally accumulates on a person. That is why you ought to carry a various pair of socks to enable them to be worn instead these pieces possess become soiled with perspiring.

There are very few real in order to tell if that is in order to be be info about the subject method a person personally. Let us face it; you absolutely going to consider this is not the right method for you, an individual might be right, so always explore the choices.

Anxiety can impact the way you live, but allow it. None of the symptoms are great to together with. Consult with your doctor about treatment procedures. Millions of Americans endure the consequences of anxiety and want therapy or medication guide control their symptoms. Your current products treat anxiety you will feel much better and have the ability to live your more freely and happily.

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