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{{enzyme
| Name = exopolyphosphatase
| EC_number = 3.6.1.11
| CAS_number = 9024-85-5
| IUBMB_EC_number = 3/6/1/11
| GO_code = 0004309
| image =
| width =
| caption =
}}
In [[enzymology]], an '''exopolyphosphatase''' ({{EC number|3.6.1.11}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:(polyphosphate)n + H<sub>2</sub>O <math>\rightleftharpoons</math> (polyphosphate)n-1 + phosphate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[(polyphosphate)n]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[(polyphosphate)n-1]] and [[phosphate]].
 
This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is '''polyphosphate phosphohydrolase'''. Other names in common use include '''metaphosphatase''', '''acid phosphoanhydride phosphohydrolase''', and '''Gra-Pase'''. This enzyme participates in [[purine metabolism]].
 
==Structural studies==
 
As of late 2007, 4 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1T6C}}, {{PDB link|1T6D}}, {{PDB link|1U6Z}}, and {{PDB link|2FLO}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = Grossman D and Lang K | date = 1962 | title = Anorganische Poly- und Metaphosphatasen sowie Polyphosphate im tierischen Zellkern | journal = Biochem. Z. | volume = 336 | pages = 351&ndash;370 }}
* {{cite journal | author = Krishman PS | date = 1952 | title = Apyrase, pyrophosphatase and metaphosphatase of Penicillium chrysogenum | journal = Arch. Biochem. Biophys. | volume = 37 | pages = 224&ndash;234 | doi = 10.1016/0003-9861(52)90180-X | pmid=14953432 | issue = 1}}
* {{cite journal | author = Malmgren H | date = 1952 | title = Enzymatic behavior of polymetaphosphate. V. Purification and specificity of the enzyme | journal = Acta Chem. Scand. | volume = 6 | pages = 16&ndash;26 | doi = 10.3891/acta.chem.scand.06-0016 | last2 = Malmgren | first2 = H. | last3 = Åkerström | first3 = Å. | last4 = Finsnes | first4 = Ernst | last5 = Sörensen | first5 = JöRgine Stene | last6 = Sörensen | first6 = Nils Andreas }}
 
{{hydrolase-stub}}
 
[[Category:EC 3.6.1]]
[[Category:Enzymes of known structure]]

Revision as of 09:41, 2 February 2014

Template:Enzyme In enzymology, an exopolyphosphatase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

(polyphosphate)n + H2O (polyphosphate)n-1 + phosphate

Thus, the two substrates of this enzyme are (polyphosphate)n and H2O, whereas its two products are (polyphosphate)n-1 and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is polyphosphate phosphohydrolase. Other names in common use include metaphosphatase, acid phosphoanhydride phosphohydrolase, and Gra-Pase. This enzyme participates in purine metabolism.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

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Template:Hydrolase-stub