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[[File:FBP Iter single.jpg|thumb|Example showing differences between filtered backprojection (right half) and iterative reconstruction method (left half)]]
'''Iterative reconstruction''' refers to [[Iteration|iterative]] [[algorithms]] used to reconstruct 2D and 3D images in certain [[Digital imaging|imaging]] techniques.
For example, in [[computed tomography]] an image must be reconstructed from projections of an object. Here, iterative reconstruction techniques are a
better, but computationally more expensive, alternative to the common [[filtered back projection]] (FBP) method, which directly calculates the image in
a single reconstruction step.<ref name="ref1">Herman, G. T., Fundamentals of computerized tomography: Image reconstruction from projection, 2nd edition, Springer, 2009</ref>
 
== Basic concepts ==
 
The reconstruction of an image from the acquired data is an [[inverse problem]]. Often, it is not possible to exactly solve the inverse
problem directly. In this case, a direct algorithm has to approximate the solution, which might cause visible reconstruction [[Digital artifact|artifacts]]
in the image. Iterative algorithms approach the correct solution using multiple iteration steps, which allows to obtain a better
reconstruction at the cost of a higher computation time.
 
In [[computed tomography]], this approach was the one first used by [[Godfrey Hounsfield|Hounsfield]]. There are a large variety of algorithms, but each starts with an assumed image, computes projections from the image, compares the original projection data and updates the image based upon the difference between the calculated and the actual projections.
 
There are typically five components to iterative image reconstruction algorithms,
e.g.
.<ref name="pwl">
J A Fessler, "Penalized weighted least-squares image reconstruction for positron emission tomography,"
IEEE Trans. on Medical Imaging, 13(2):290-300, June 1994.
</ref>
# An object model that expresses the unknown continuous-space function <math>f(r)</math> that is to be reconstructed in terms of a finite series with unknown coefficients that must be estimated from the data.
# A system model that relates the unknown object to the "ideal" measurements that would be recorded in the absence of measurement noise.  Often this is a linear model of the form <math>\mathbf{A}x</math>.
# A [[statistical model]] that describes how the noisy measurements vary around their ideal values. Often [[Gaussian noise]] or [[Poisson statistics]] are assumed.
# A [[Loss function|cost function]] that is to be minimized to estimate the image coefficient vector. Often this cost function includes some form of [[regularization]]. Sometimes the regularization is based on [[Markov random fields]].
# An [[algorithm]], usually iterative, for minimizing the cost function, including some initial estimate of the image and some stopping criterion for terminating the iterations.
 
== Advantages ==
 
The advantages of the iterative approach include improved insensitivity to [[signal noise|noise]] and capability of reconstructing an [[Optimization (mathematics)|optimal]] image in the case of incomplete data. The method has been applied in emission tomography modalities like [[SPECT]] and [[Positron emission tomography|PET]], where there is significant attenuation along ray paths and [[noise statistics]] are relatively poor.
 
As another example, it is considered superior when one does not have a large set of projections
available, when the projections are not distributed uniformly in angle, or when the projections are sparse or missing at certain orientations. These scenarios may occur in [[intraoperative]] CT, in [[cardiac]] CT, or when metal [[artifact (observational)|artifacts]]
<ref name="mdt">
FE Boas and D Fleischmann. "[http://radiology.rsna.org/content/early/2011/02/17/radiol.11101782.abstract Evaluation of two iterative techniques for reducing metal artifacts in computed tomography.]" Radiology, {{doi|10.1148/radiol.11101782}}, 2011.
</ref>
require the exclusion of some portions of the projection data.
 
In [[Magnetic Resonance Imaging]] it can be used to reconstruct images from data acquired with multiple receive coils and with sampling patterns different from the conventional Cartesian grid<ref>Pruessmann, K. P., Weiger, M., Börnert, P. and Boesiger, P. (2001), Advances in sensitivity encoding with arbitrary k-space trajectories. Magnetic Resonance in Medicine, 46: 638–651. {{doi|10.1002/mrm.1241}}</ref> and allows the use of improved regularization techniques (e.g. [[total variation]])<ref>Block, K. T., Uecker, M. and Frahm, J. (2007), Undersampled radial MRI with multiple coils. Iterative image reconstruction using a total variation constraint. Magnetic Resonance in Medicine, 57: 1086–1098. {{doi|10.1002/mrm.21236}}</ref> or an extended modeling of physical processes<ref>Fessler, J. (2010) Model-based Image Reconstruction for MRI. Signal Processing Magazine, IEEE 27:81-89</ref> to improve the reconstruction. For example, with iterative algorithms it is possible to
reconstruct images from data acquired in a very short time as required for [[Real-time MRI]].<ref name=uecker2010>M Uecker, S Zhang, D Voit, A Karaus, KD Merboldt, J Frahm (2010a) Real-time MRI at a resolution of 20 ms. NMR Biomed 23: 986-994, {{doi|10.1002/nbm.1585}}</ref>
 
Here is an example that illustrates the benefits of iterative image reconstruction for cardiac MRI.<ref name="ilyas Uyanik 2013">I Uyanik, P Lindner, D Shah, N Tsekos I Pavlidis (2013) Applying a Level Set Method for Resolving Physiologic Motions in Free-Breathing and Non-gated Cardiac MRI. FIMH, 2013, [http://www.cpl.uh.edu/files/publications/conf_paper_videos/c66.pdf]</ref>
 
[[File:Heart-direct-vs-iterative-reconstruction.png|frame|A single frame from a [[Real-time MRI]] movie of a [[human heart]]. a) direct reconstruction b) iterative (nonlinear inverse) reconstruction<ref name=uecker2010 />]]
 
==See also==
 
*[[Tomographic reconstruction]]
*[[Tomogram]]
*[[Computed Tomography]]
*[[Magnetic Resonance Imaging]]
*[[Inverse problem]]
*[[Osem (mathematics)|Osem]]
*[[Deconvolution]]
 
==References==
<references/>
 
{{commons category|Iterative reconstruction}}
 
{{DEFAULTSORT:Iterative Reconstruction}}
[[Category:Medical imaging]]

Latest revision as of 17:11, 24 November 2014

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