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{{DEFAULTSORT:Acquired Immune Deficiency Syndrome}}
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==Lipodystrophy==
Do not see what part of the paper supports this "Those who have not been treated with HAART have a higher rates of these metabolic problems suggesting that HIV itself may have an negative impact on cardiovascular system.<ref>{{cite journal |author=Troll JG|title=Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection|journal=Curr Atheroscler Rep |volume=13 |issue=1 |pages=51-6 |year=2011 |pmid=21181310  |pmc=3018260|doi=10.1007/s11883-010-0152-1}}</ref>"
{{reflist}}
[[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 16:10, 5 December 2013 (UTC)
:Emailed you the specifics and let you know via email/talk page. [[User:TylerDurden8823|TylerDurden8823]] ([[User talk:TylerDurden8823|talk]]) 20:43, 5 December 2013 (UTC)
 
== Semi-protected edit request on 22 December 2013 ==
 
{{edit semi-protected|<!-- Page to be edited -->|answered=yes}}
<!-- Begin request -->
I'd like to make an edit request:
 
under the section of "Discovery", I believe that Francoise Barre-Sinoussi should receive equal credit as Luc Montagnier in discovering HIV, as they received the Nobel Prize for it jointly.
 
 
Thank you.  <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/147.26.87.13|147.26.87.13]] ([[User talk:147.26.87.13|talk]]) 02:18, 7 January 2014 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->
 
 
Hello,
 
In light of the new developments in our understanding of how HIV kills CD4 T cells
 
1. I would like to add these relevant references:
 
To the sentence: "It directly and indirectly destroys CD4+ T cells.[57]" please add <ref>http://www.cell.com/abstract/S0092-8674(10)01245-6</ref><ref>http://www.nature.com/nature/journal/vnfv/ncurrent/full/nature12940.html</ref>
 
2. To the section Pathophysiology I would request to add:
 
After the sentence: During the chronic phase, the consequences of generalized immune activation coupled with the gradual loss of the ability of the immune system to generate new T cells appear to account for the slow decline in CD4+ T cell numbers.[69]:
I would request to add the following sentences:
 
Recent studies<ref>http://www.nature.com/nature/journal/vnfv/ncurrent/full/nature12940.html</ref><ref>http://www.sciencemag.org/content/early/2013/12/18/science.1243640</ref> demonstrate that lymphoid CD4 T cells, abortively infected by HIV-1, die by caspase-1-mediated pyroptosis, a highly inflammatory form of programmed cell death. The DNA sensor IFI16 was shown to detect HIV DNA and triggers such cell death. Depletion of CD4 T-cell depletion and inflammation are signature events that propel HIV disease progression to AIDS. Cell death by pyroptosis appears to create a pathogenic vicious cycle in which dying CD4 T cells release inflammatory signals that attract more cells into the infected lymphoid tissues to die and to produce chronic inflammation and tissue injury.
 
Thank you, and Happy Holidays.
 
<!-- End request -->
[[Special:Contributions/71.135.167.64|71.135.167.64]] ([[User talk:71.135.167.64|talk]]) 21:34, 22 December 2013 (UTC)
::We typically use [[review articles]] rather than primary sources per [[WP:MEDRS]]. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 21:50, 22 December 2013 (UTC)
:[[File:Red information icon with gradient background.svg|20px|link=|alt=]] '''Not done:'''<!-- Template:ESp --> per above. --[[User:Mdann52|<span style="color:Green">'''Mdann'''</span>]][[Special:Contributions/Mdann52|<span style="color:Red">'''52'''</span>]]<small>[[User talk:Mdann52|<span style="color:Maroon">''talk to me!''</span>]]</small> 14:12, 6 January 2014 (UTC)
 
== Probable cure for AIDS ==
 
There's probably an experimental ''cure'' for AIDS, which is the [[stem cell]].
 
There is a news article saying that two men were functionally ''cured'' of AIDS while they were undergoing a [[stem cell therapy]] to treat their lymphomas. In July 2012, Henrich had reported that the two men had no HIVs at their blood.
 
Source: {{cite web|title=Two men "cured" of HIV no longer taking treatments|url=http://www.cbsnews.com/news/two-men-cured-of-hiv-no-longer-taking-treatments|first=Michelle|last=Castillo|website=CBS News|date=3 July 2013|accessdate=12 January 2014}}
 
[[Special:Contributions/112.198.90.25|112.198.90.25]] ([[User talk:112.198.90.25|talk]]) 09:24, 12 January 2014 (UTC)
::We use secondary sources. Yes interested but no not a general "cure" [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 16:57, 12 January 2014 (UTC)
 
== AIDS Came from Eating Monkeys ==


Scientists from the University of Nottingham found that two strains of an HIV-like disease, SIV, has been discovered dormant in chimpanzees. Humans later caught the disease after hunting and eating the infected chimps. In humans, the disease morphed into HIV-AIDS, which reportedly has killed over 20 million people, mostly in Africa where eating monkey flesh often practiced <ref>http://www.thenazareneway.com/aids_came_from_monkeys.htm</ref>  <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/195.5.27.63|195.5.27.63]] ([[User talk:195.5.27.63|talk]]) 14:07, 19 January 2014 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->
== Paget's 1904 drawing ==


== Lead ==
Am I alone in looking at this drawing and seeing it as a drawing of Clive Merrison? Either it is amazing how much Clive resembles the drawing or it questions if this is really a 1904 drawing?
The lead says "AIDS is considered a pandemic", this should be rephrased as "HIV/AIDS is considered a pandemic", which is the expression that's also used in the given source. The point is that not all HIV-positive people will progress to AIDS. We should really be careful not to mix up the two terms in this article. Can someone change this please, as I am unable to edit the article. [[User:Chakalacka|Chakalacka]] ([[User talk:Chakalacka|talk]]) 18:05, 30 January 2014 (UTC)
I assume we all know that Clive Merrison has portrayed Holmes on radio more completely than any other actor?  <small><span class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:PeterM88|PeterM88]] ([[User talk:PeterM88|talk]] • [[Special:Contributions/PeterM88|contribs]]) 07:14, 4 September 2013 (UTC)</span></small><!-- Template:Unsigned --> <!--Autosigned by SineBot-->
:So Paget not only predicted the future, but he could also see how someone would look on the radio.  Most singularly unique! ;)


{{done}} -- [[User:Scray|Scray]] ([[User talk:Scray|talk]]) 18:20, 30 January 2014 (UTC)
== Surname ==


::Since we are already at it, this sentence in the Virology section should also be fixed: "HIV is the cause of the spectrum of disease known as HIV/AIDS.". It just doesn't make sense. Maybe "HIV is the cause of the disease known as AIDS." or perhaps "HIV is the cause of a spectrum of diseases known as AIDS." [[User:Chakalacka|Chakalacka]] ([[User talk:Chakalacka|talk]]) 18:38, 30 January 2014 (UTC)
: [[Talk:Arthur Conan Doyle/Archive 1#Doyle or Conan Doyle?]] (2006–2008)
:::There is also "acute HIV" which is a disease caused by the HIV virus. So I think it is okay the way it is. The spectrum is HIV/AIDS. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 18:46, 30 January 2014 (UTC)
: [[Talk:Arthur Conan Doyle/Archive 1#Conan Doyle or Doyle?]] (2007–2009)
::::Has "acute HIV" actually been characterized/defined as a disease? I'm not a doc but I am wondering. Either way, I feel that the current sentence in a nutshell says "HIV is the cause of HIV" and somehow that seems more confusing than clarifying. [[User:Chakalacka|Chakalacka]] ([[User talk:Chakalacka|talk]]) 13:09, 31 January 2014 (UTC)
:::::Yes it is a disease. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 14:40, 31 January 2014 (UTC)


== Semi-protected edit request on 31 January 2014 ==
In effect I continue those two old threads. The rest of this note (including my signature and timestamp) is copied from [[Talk:Adrian Conan Doyle]]. -P64 (22:05)
----
''begin copy''


{{Edit semi-protected|<!-- Page to be edited -->|answered=yes}}
We call him Adrian Doyle here, Conan Doyle there, Doyle elsewhere, and instruct to sort by 'Conandoyle'. Libraries make Doyle the surname.[http://viaf.org/viaf/100257437/]
<!-- Begin request -->


<!-- End request -->
In the father's biography we provide some discussion [[Arthur Conan Doyle#Name]] with the weight of evidence or practice heavily on the 'Doyle' side, and we use 'Doyle' in running prose. But again we instruct to sort by 'Conandoyle'. Libraries make Doyle the surname.[http://viaf.org/viaf/65283845/]
[[Special:Contributions/27.124.18.34|27.124.18.34]] ([[User talk:27.124.18.34|talk]]) 13:48, 31 January 2014 (UTC)
The Sir ACD Literary Estate official website[ uses 'Conan Doyle' on the homepage, where it does not use 'Doyle' alone.[http://www.sherlockholmesonline.org/TheEstate/] The NYT obituary  headline writer uses 'Conan Doyle' but the text uses 'Lady Doyle'.[http://www.nytimes.com/learning/general/onthisday/bday/0522.html]


:What actually? [[User:Noteswork|Noteswork]] ([[User talk:Noteswork|talk]]) 13:51, 31 January 2014 (UTC)
--[[User:P64|P64]] ([[User talk:P64|talk]]) 21:49, 2 October 2013 (UTC)


== "These" versus "The vast majority of these" ==
''end copy''
----
:"The Sir ACD Literary Estate" isn't connected to the Doyle family heirs and shouldn't be taken as any definitive statement (and even if there were an official website, it could use both depending on the copywriter; not everyone gets concerned about the same matters). Without wanting to detour the ACD copyrights have been a source of dispute for decades ultimately stemming from different children of ACD and various sales & reclaims, and that site is based on an ownership claim stemming from a 1970s sale outside the family (and disputes the subsequent termination of transfer). [[User:Timrollpickering|Timrollpickering]] ([[User talk:Timrollpickering|talk]]) 23:05, 2 October 2013 (UTC)


Disagreement with [https://en.wikipedia.org/w/index.php?title=HIV/AIDS&curid=5069516&diff=594374423&oldid=593841565 this edit] that I wanted to discuss rather than just revert.  
::Just to ensure we are consistent, if nothing else, I've put the surname only mentions to Doyle, rather than Conan Doyle. It's a moot point which should be the preferred style, but we do need to stick to one over the other. Given what we say in the [[Arthur Conan Doyle#Name|name section]], Doyle seems to be as good a place as any. - [[User:SchroCat|SchroCat]] ([[User talk:SchroCat|talk]]) 07:42, 14 October 2013 (UTC)


The full phrase in question, with the disputed part bolded, is:<blockquote>A small group of individuals continue to dispute the connection between HIV and AIDS,[228] the existence of HIV itself, or the validity of HIV testing and treatment methods.[229][230] '''The vast majority of these claims''', known as AIDS denialism, have been examined and rejected by the scientific community.</blockquote>
::: I made the same change, among other things, at [[Adrian Conan Doyle]]. Thus Arthur and Adrian would be listed side-by-side in categories {{c|English mystery writers}} and {{c|English short story writers}} --but Sir Arthur is exclusively Scottish. Anyway they both show up under D in most categories --as daughter [[Jean Conan Doyle]] does not, as we explain in her lead.
As it looks now, it is implied that there exist some disputes about HIV and its relationship with AIDS that have been examined and accepted. This is most certainly not the case: EVERY such denialist claim that has been investigated has been rejected, quite firmly. While "These claims" is technically imprecise, it does not give a false impression and is significantly more correct. Thoughts? [[User:TechBear|<font color="green">'''TechBear'''</font>]] &#124; [[User talk:TechBear|Talk]] &#124; [[Special:Contributions/TechBear|Contributions]] 15:06, 7 February 2014 (UTC)
:I reverted it to say that all denialist claims are answered. There are not any [[WP:RS|reliable sources]] presenting unanswered denialist claims. There is no controversy in the scientific or medical community. Anyone who wishes to state otherwise should present a source making a claim which has not been answered. So far as I know, by the late 1990s the debates had resolved in the scientific and medical communities, and no claims have been made since then. See [[WP:MEDRS|Wikipedia's guide to reliable sources for medicine]] for information about how to present medical claims. [[User:Bluerasberry|<span style="background:#cedff2;color:#11e">''' Blue Rasberry '''</span>]][[User talk:Bluerasberry|<span style="cursor:help"><span style="background:#cedff2;color:#11e">(talk)</span></span>]] 15:49, 7 February 2014 (UTC)
::What we had before which was "These claims" was perfectly clear. Thus restored to that. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 18:03, 7 February 2014 (UTC)


== Removing very odd opinion from lead. ==
----


People are free to their opinions but I don't think they are needed in this Wikipedia article.  I will be removing the line "The disease has also become subject to many controversies involving religion." Considering most people on the planet are religious, and most have different views of all subject matter, anything could be "subject to many controversies involving religion".[[User:Mantion|Mantion]] ([[User talk:Mantion|talk]]) 06:00, 10 February 2014 (UTC)
::: By the way, the US national library reports many "Sources" of surname usage for Arthur and his Lady.[http://id.loc.gov/authorities/names/n79082292.html]  
:It's not an opinion or odd, and it's in the lead because it summarizes significant aspects of the article...per [[WP:Lead]]. [[User:Flyer22|Flyer22]] ([[User talk:Flyer22|talk]]) 06:05, 10 February 2014 (UTC)
::: --[[User:P64|P64]] ([[User talk:P64|talk]]) 20:08, 14 October 2013 (UTC)
::Yes there have been some controversies revolving around organized religion. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 10:14, 10 February 2014 (UTC)


== Congenital HIV/AIDS infection ==
==Edit request==
{{Edit semi-protected|ans=yes}}
Arthur Conan Doyle is distantly related to Bram Stoker the author <ref>http://en.wikipedia.org/wiki/Bram_Stoker</ref>


No article on it. Surprised. Anyone smart?
[[Special:Contributions/80.44.233.127|80.44.233.127]] ([[User talk:80.44.233.127|talk]]) 17:29, 20 November 2013 (UTC)
:How, exactly, does a newborn with HIV differ substantially from someone who contracts the virus later in life? Can you refer editors to [[WP:RS|reliable]], [[WP:3PARTY|third-party]] sources that detail the differences? [[User:TechBear|<font color="green">'''TechBear'''</font>]] &#124; [[User talk:TechBear|Talk]] &#124; [[Special:Contributions/TechBear|Contributions]] 22:16, 12 February 2014 (UTC)


==Red ribbon==
[[File:Red information icon with gradient background.svg|20px|link=|alt=]] '''Not done:''' please make your request in a "change X to Y" format.<!-- Template:ESp --> Also, you need a [[WP:RS|reliable source]] for this. Wikipedia is not a reliable source, but you may be able to find the source of that claim in the references for that article. Thanks, [[User:Celestra|Celestra]] ([[User talk:Celestra|talk]]) 19:55, 20 November 2013 (UTC)
Consider it a better image for the lead. Thus restored. [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) (if I write on your page reply on mine) 19:02, 27 February 2014 (UTC)

Revision as of 17:54, 19 August 2014

User:MiszaBot/config

Template:ArticleHistory Template:Vital article Template:WikiProjectBannerShell Template:Archive box

Paget's 1904 drawing

Am I alone in looking at this drawing and seeing it as a drawing of Clive Merrison? Either it is amazing how much Clive resembles the drawing or it questions if this is really a 1904 drawing? I assume we all know that Clive Merrison has portrayed Holmes on radio more completely than any other actor? — Preceding unsigned comment added by PeterM88 (talkcontribs) 07:14, 4 September 2013 (UTC)

So Paget not only predicted the future, but he could also see how someone would look on the radio. Most singularly unique! ;)

Surname

Talk:Arthur Conan Doyle/Archive 1#Doyle or Conan Doyle? (2006–2008)
Talk:Arthur Conan Doyle/Archive 1#Conan Doyle or Doyle? (2007–2009)

In effect I continue those two old threads. The rest of this note (including my signature and timestamp) is copied from Talk:Adrian Conan Doyle. -P64 (22:05)


begin copy

We call him Adrian Doyle here, Conan Doyle there, Doyle elsewhere, and instruct to sort by 'Conandoyle'. Libraries make Doyle the surname.[1]

In the father's biography we provide some discussion Arthur Conan Doyle#Name with the weight of evidence or practice heavily on the 'Doyle' side, and we use 'Doyle' in running prose. But again we instruct to sort by 'Conandoyle'. Libraries make Doyle the surname.[2]

The Sir ACD Literary Estate official website[ uses 'Conan Doyle' on the homepage, where it does not use 'Doyle' alone.[3] The NYT obituary headline writer uses 'Conan Doyle' but the text uses 'Lady Doyle'.[4]

--P64 (talk) 21:49, 2 October 2013 (UTC)

end copy


"The Sir ACD Literary Estate" isn't connected to the Doyle family heirs and shouldn't be taken as any definitive statement (and even if there were an official website, it could use both depending on the copywriter; not everyone gets concerned about the same matters). Without wanting to detour the ACD copyrights have been a source of dispute for decades ultimately stemming from different children of ACD and various sales & reclaims, and that site is based on an ownership claim stemming from a 1970s sale outside the family (and disputes the subsequent termination of transfer). Timrollpickering (talk) 23:05, 2 October 2013 (UTC)
Just to ensure we are consistent, if nothing else, I've put the surname only mentions to Doyle, rather than Conan Doyle. It's a moot point which should be the preferred style, but we do need to stick to one over the other. Given what we say in the name section, Doyle seems to be as good a place as any. - SchroCat (talk) 07:42, 14 October 2013 (UTC)
I made the same change, among other things, at Adrian Conan Doyle. Thus Arthur and Adrian would be listed side-by-side in categories Template:C and Template:C --but Sir Arthur is exclusively Scottish. Anyway they both show up under D in most categories --as daughter Jean Conan Doyle does not, as we explain in her lead.

By the way, the US national library reports many "Sources" of surname usage for Arthur and his Lady.[5]
--P64 (talk) 20:08, 14 October 2013 (UTC)

Edit request

Template:Edit semi-protected Arthur Conan Doyle is distantly related to Bram Stoker the author [1]

80.44.233.127 (talk) 17:29, 20 November 2013 (UTC)

Not done: please make your request in a "change X to Y" format. Also, you need a reliable source for this. Wikipedia is not a reliable source, but you may be able to find the source of that claim in the references for that article. Thanks, Celestra (talk) 19:55, 20 November 2013 (UTC)