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Lipodystrophy
Do not see what part of the paper supports this "Those who have not been treated with HAART have a higher rates of these metabolic problems suggesting that HIV itself may have an negative impact on cardiovascular system.[1]" 43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro. Doc James (talk · contribs · email) (if I write on your page reply on mine) 16:10, 5 December 2013 (UTC)
- Emailed you the specifics and let you know via email/talk page. TylerDurden8823 (talk) 20:43, 5 December 2013 (UTC)
Semi-protected edit request on 22 December 2013
Template:Edit semi-protected I'd like to make an edit request:
under the section of "Discovery", I believe that Francoise Barre-Sinoussi should receive equal credit as Luc Montagnier in discovering HIV, as they received the Nobel Prize for it jointly.
Thank you. — Preceding unsigned comment added by 147.26.87.13 (talk) 02:18, 7 January 2014 (UTC)
Hello,
In light of the new developments in our understanding of how HIV kills CD4 T cells
1. I would like to add these relevant references:
To the sentence: "It directly and indirectly destroys CD4+ T cells.[57]" please add [2][3]
2. To the section Pathophysiology I would request to add:
After the sentence: During the chronic phase, the consequences of generalized immune activation coupled with the gradual loss of the ability of the immune system to generate new T cells appear to account for the slow decline in CD4+ T cell numbers.[69]: I would request to add the following sentences:
Recent studies[4][5] demonstrate that lymphoid CD4 T cells, abortively infected by HIV-1, die by caspase-1-mediated pyroptosis, a highly inflammatory form of programmed cell death. The DNA sensor IFI16 was shown to detect HIV DNA and triggers such cell death. Depletion of CD4 T-cell depletion and inflammation are signature events that propel HIV disease progression to AIDS. Cell death by pyroptosis appears to create a pathogenic vicious cycle in which dying CD4 T cells release inflammatory signals that attract more cells into the infected lymphoid tissues to die and to produce chronic inflammation and tissue injury.
Thank you, and Happy Holidays.
71.135.167.64 (talk) 21:34, 22 December 2013 (UTC)
Not done: per above. --Mdann52talk to me! 14:12, 6 January 2014 (UTC)
Probable cure for AIDS
There's probably an experimental cure for AIDS, which is the stem cell.
There is a news article saying that two men were functionally cured of AIDS while they were undergoing a stem cell therapy to treat their lymphomas. In July 2012, Henrich had reported that the two men had no HIVs at their blood.
Source: Template:Cite web
112.198.90.25 (talk) 09:24, 12 January 2014 (UTC)
AIDS Came from Eating Monkeys
Scientists from the University of Nottingham found that two strains of an HIV-like disease, SIV, has been discovered dormant in chimpanzees. Humans later caught the disease after hunting and eating the infected chimps. In humans, the disease morphed into HIV-AIDS, which reportedly has killed over 20 million people, mostly in Africa where eating monkey flesh often practiced [6] — Preceding unsigned comment added by 195.5.27.63 (talk) 14:07, 19 January 2014 (UTC)
Lead
The lead says "AIDS is considered a pandemic", this should be rephrased as "HIV/AIDS is considered a pandemic", which is the expression that's also used in the given source. The point is that not all HIV-positive people will progress to AIDS. We should really be careful not to mix up the two terms in this article. Can someone change this please, as I am unable to edit the article. Chakalacka (talk) 18:05, 30 January 2014 (UTC)
Template:Done -- Scray (talk) 18:20, 30 January 2014 (UTC)
- Since we are already at it, this sentence in the Virology section should also be fixed: "HIV is the cause of the spectrum of disease known as HIV/AIDS.". It just doesn't make sense. Maybe "HIV is the cause of the disease known as AIDS." or perhaps "HIV is the cause of a spectrum of diseases known as AIDS." Chakalacka (talk) 18:38, 30 January 2014 (UTC)
- There is also "acute HIV" which is a disease caused by the HIV virus. So I think it is okay the way it is. The spectrum is HIV/AIDS. Doc James (talk · contribs · email) (if I write on your page reply on mine) 18:46, 30 January 2014 (UTC)
- Has "acute HIV" actually been characterized/defined as a disease? I'm not a doc but I am wondering. Either way, I feel that the current sentence in a nutshell says "HIV is the cause of HIV" and somehow that seems more confusing than clarifying. Chakalacka (talk) 13:09, 31 January 2014 (UTC)
- There is also "acute HIV" which is a disease caused by the HIV virus. So I think it is okay the way it is. The spectrum is HIV/AIDS. Doc James (talk · contribs · email) (if I write on your page reply on mine) 18:46, 30 January 2014 (UTC)
- Since we are already at it, this sentence in the Virology section should also be fixed: "HIV is the cause of the spectrum of disease known as HIV/AIDS.". It just doesn't make sense. Maybe "HIV is the cause of the disease known as AIDS." or perhaps "HIV is the cause of a spectrum of diseases known as AIDS." Chakalacka (talk) 18:38, 30 January 2014 (UTC)
Semi-protected edit request on 31 January 2014
27.124.18.34 (talk) 13:48, 31 January 2014 (UTC)
"These" versus "The vast majority of these"
Disagreement with this edit that I wanted to discuss rather than just revert.
The full phrase in question, with the disputed part bolded, is:
A small group of individuals continue to dispute the connection between HIV and AIDS,[228] the existence of HIV itself, or the validity of HIV testing and treatment methods.[229][230] The vast majority of these claims, known as AIDS denialism, have been examined and rejected by the scientific community.
As it looks now, it is implied that there exist some disputes about HIV and its relationship with AIDS that have been examined and accepted. This is most certainly not the case: EVERY such denialist claim that has been investigated has been rejected, quite firmly. While "These claims" is technically imprecise, it does not give a false impression and is significantly more correct. Thoughts? TechBear | Talk | Contributions 15:06, 7 February 2014 (UTC)
- I reverted it to say that all denialist claims are answered. There are not any reliable sources presenting unanswered denialist claims. There is no controversy in the scientific or medical community. Anyone who wishes to state otherwise should present a source making a claim which has not been answered. So far as I know, by the late 1990s the debates had resolved in the scientific and medical communities, and no claims have been made since then. See Wikipedia's guide to reliable sources for medicine for information about how to present medical claims. Blue Rasberry (talk) 15:49, 7 February 2014 (UTC)
Removing very odd opinion from lead.
People are free to their opinions but I don't think they are needed in this Wikipedia article. I will be removing the line "The disease has also become subject to many controversies involving religion." Considering most people on the planet are religious, and most have different views of all subject matter, anything could be "subject to many controversies involving religion".Mantion (talk) 06:00, 10 February 2014 (UTC)
- It's not an opinion or odd, and it's in the lead because it summarizes significant aspects of the article...per WP:Lead. Flyer22 (talk) 06:05, 10 February 2014 (UTC)
Congenital HIV/AIDS infection
No article on it. Surprised. Anyone smart?
- How, exactly, does a newborn with HIV differ substantially from someone who contracts the virus later in life? Can you refer editors to reliable, third-party sources that detail the differences? TechBear | Talk | Contributions 22:16, 12 February 2014 (UTC)
Red ribbon
Consider it a better image for the lead. Thus restored. Doc James (talk · contribs · email) (if I write on your page reply on mine) 19:02, 27 February 2014 (UTC)
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- ↑ http://www.nature.com/nature/journal/vnfv/ncurrent/full/nature12940.html
- ↑ http://www.nature.com/nature/journal/vnfv/ncurrent/full/nature12940.html
- ↑ http://www.sciencemag.org/content/early/2013/12/18/science.1243640
- ↑ http://www.thenazareneway.com/aids_came_from_monkeys.htm