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| {{enzyme
| | http://www.auto-r.by<br><br>+375 29 7777274 МТС<br>+375 44 7777274 VELCOM<br>+375 25 7777274 LIFE<br>+375 29 1611177 VELCOM<br>+375 29 5611177 МТС<br>+375 17 2029675 TEL/FAX<br><br>skype: auto.r <br><br>mail:auto-r@auto-r.by<br><br>mail_cc:auto-r@tut.by <br><br>Наш адрес: г. Минск ул. Тимошенко дом 8 офис 26<br><br>my web site ... заказать автозапчасти онлайн ([http://auto-r.by/to/ auto-r.by]) |
| | Name = uridine kinase
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| | EC_number = 2.7.1.48
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| | CAS_number = 9026-39-5
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| | IUBMB_EC_number = 2/7/1/48
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| | GO_code = 0004849
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| | image =
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| }}
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| In [[enzymology]], an '''uridine kinase''' ({{EC number|2.7.1.48}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :ATP + uridine <math>\rightleftharpoons</math> ADP + UMP
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[uridine]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[uridine monophosphate|UMP]].
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| This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with an alcohol group as acceptor. The systematic name of this enzyme class is '''ATP:uridine 5'-phosphotransferase'''. Other names in common use include '''pyrimidine ribonucleoside kinase''', '''uridine-cytidine kinase''', '''uridine kinase (phosphorylating)''', and '''uridine phosphokinase'''. This enzyme participates in [[pyrimidine metabolism]].
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| ==Structural studies==
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| As of late 2007, 8 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1UDW}}, {{PDB link|1UEI}}, {{PDB link|1UEJ}}, {{PDB link|1UFQ}}, {{PDB link|1UJ2}}, {{PDB link|1XRJ}}, {{PDB link|2JEO}}, and {{PDB link|2UVQ}}.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Orengo A | date = 1969 | title = Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor | journal = J. Biol. Chem. | volume = 244 | pages = 2204–9 | pmid = 5782006 | issue = 8 }}
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| * {{cite journal | author = Skold O | date = 1960 | title = Uridine kinase from Erlich ascites tumor: purification and properties | journal = J. Biol. Chem. | volume = 235 | pages = 3273–3279 }}
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| {{enzyme-stub}}
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| [[Category:EC 2.7.1]] | |
| [[Category:Enzymes of known structure]]
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http://www.auto-r.by
+375 29 7777274 МТС
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+375 25 7777274 LIFE
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