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{{enzyme
| Name = L-xylulose reductase
| EC_number = 1.1.1.10
| CAS_number =
| IUBMB_EC_number = 1/1/1/10
| GO_code =
| image =
| width =
| caption =
}}
{{protein
|Name=dicarbonyl/L-xylulose reductase
|caption=
|image=Human xylulose reductase holoenzyme.png
|width=
|HGNCid=18985
|Symbol=DCXR
|AltSymbols=
|EntrezGene=51181
|OMIM=608347
|RefSeq=NM_016286
|UniProt=Q7Z4W1
|PDB=
|ECnumber=1.1.1.10
|Chromosome=17
|Arm=q
|Band=25.3
|LocusSupplementaryData=
}}
In [[enzymology]], an '''L-xylulose reductase''' ({{EC number|1.1.1.10}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:xylitol + NADP<sup>+</sup> <math>\rightleftharpoons</math> L-xylulose + NADPH + H<sup>+</sup>
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[xylitol]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[D-xylulose]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
 
<gallery>
Image:Xylulose.png|[[Xylulose]]
Image:Xylitol.png|[[Xylitol]] (Note conversion of [[ketone]] to [[alcohol]])
</gallery>
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''xylitol:NADP<sup>+</sup> 2-oxidoreductase (L-xylulose-forming)'''.
 
==Pathology==
A deficiency is responsible for [[pentosuria]].
 
==References==
{{reflist|1}}
 
==External links==
* {{MeshName|L-xylulose+reductase}}
 
{{Alcohol oxidoreductases}}
 
[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of known structure]]
 
{{1.1.1-enzyme-stub}}

Latest revision as of 07:31, 23 January 2014

Template:Enzyme Template:Protein In enzymology, an L-xylulose reductase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

xylitol + NADP+ L-xylulose + NADPH + H+

Thus, the two substrates of this enzyme are xylitol and NADP+, whereas its 3 products are D-xylulose, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is xylitol:NADP+ 2-oxidoreductase (L-xylulose-forming).

Pathology

A deficiency is responsible for pentosuria.

References

43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.

External links

Template:Alcohol oxidoreductases

Template:1.1.1-enzyme-stub