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'''Blood gas tension''' refers to the [[partial pressure]] of gases in [[blood]].<ref name="pmid9563770">{{cite journal| author=Severinghaus JW, Astrup P, Murray JF| title=Blood gas analysis and critical care medicine. | journal=Am J Respir Crit Care Med | year= 1998 | volume= 157 | issue= 4 Pt 2 | pages= S114-22 | pmid=9563770 | doi= 10.1164/ajrccm.157.4.nhlb1-9| pmc= | url= }}</ref>  There are several significant purposes for measuring gas tension;<ref name="pmid16215371">{{cite journal| author=Bendjelid K, Schütz N, Stotz M, Gerard I, Suter PM, Romand JA| title=Transcutaneous PCO2 monitoring in critically ill adults: clinical evaluation of a new sensor. | journal=Crit Care Med | year= 2005 | volume= 33 | issue= 10 | pages= 2203–6 | pmid=16215371 | doi= 10.1097/01.ccm.0000181734.26070.26| pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16215371  }}</ref> the most common gas tensions measured are oxygen tension<ref name="pmid14736638">{{cite journal| author=Yildizdaş D, Yapicioğlu H, Yilmaz HL, Sertdemir Y| title=Correlation of simultaneously obtained capillary, venous, and arterial blood gases of patients in a paediatric intensive care unit. | journal=Arch Dis Child | year= 2004 | volume= 89 | issue= 2 | pages= 176–80 | pmid=14736638 | doi= 10.1136/adc.2002.016261| pmc=1719810 | url= }}</ref> (P<sub>x</sub>O<sub>2</sub>), the carbon dioxide tension<ref name="pmid14736638"/> (P<sub>x</sub>CO<sub>2</sub>) and carbon monoxide tension<ref name="pmid14736638"/> (P<sub>x</sub>CO).  The ''x'' factor in the symbol for each would be replaced by the source of the gas being measured; "''a''" meaning [[artery|arterial]],<ref name="pmid14736638"/> "''A''" being alveolar,<ref name="pmid14736638"/> "''v''" being [[vein|venous]],<ref name="pmid14736638"/> "''c''" being [[capillary]].<ref name="pmid14736638"/>
This is a preview for the new '''MathML rendering mode''' (with SVG fallback), which is availble in production for registered users.


==Oxygen tension==
If you would like use the '''MathML''' rendering mode, you need a wikipedia user account that can be registered here [[https://en.wikipedia.org/wiki/Special:UserLogin/signup]]
;Arterial blood oxygen tension (normal)
* Only registered users will be able to execute this rendering mode.
'''P<sub>a</sub>O<sub>2</sub>''' — Partial pressure of oxygen at sea level (765 mmHg) in arterial blood is between 75 mmHg and 100 mmHg.<ref name="pmid9390851">{{cite journal| author=Shapiro BA| title=Temperature correction of blood gas values. | journal=Respir Care Clin N Am | year= 1995 | volume= 1 | issue= 1 | pages= 69–76 | pmid=9390851 | doi= | pmc= | url= }}</ref><ref name="pmid17652681">{{cite journal| author=Malatesha G, Singh NK, Bharija A, Rehani B, Goel A| title=Comparison of arterial and venous pH, bicarbonate, PCO2 and PO2 in initial emergency department assessment. | journal=Emerg Med J | year= 2007 | volume= 24 | issue= 8 | pages= 569–71 | pmid=17652681 | doi=10.1136/emj.2007.046979 | pmc=2660085  }}</ref><ref name="pmid14569318">{{cite journal| author=Chu YC, Chen CZ, Lee CH, Chen CW, Chang HY, Hsiue TR| title=Prediction of arterial blood gas values from venous blood gas values in patients with acute respiratory failure receiving mechanical ventilation. | journal=J Formos Med Assoc | year= 2003 | volume= 102 | issue= 8 | pages= 539–43 | pmid=14569318 | doi= | pmc= | url= }}</ref>
* Note: you need not enter a email address (nor any other private information). Please do not use a password that you use elsewhere.


;Venous blood oxygen tension (normal)
Registered users will be able to choose between the following three rendering modes:  
'''P<sub>v</sub>O<sub>2</sub>''' — Oxygen tension in venous blood at sea level is between 30 mmHg and 40 mmHg.<ref name="pmid14569318"/><ref name="pmid20018607">{{cite journal| author=Walkey AJ, Farber HW, O'Donnell C, Cabral H, Eagan JS, Philippides GJ| title=The accuracy of the central venous blood gas for acid-base monitoring. | journal=J Intensive Care Med | year= 2010 | volume= 25 | issue= 2 | pages= 104–10 | pmid=20018607 | doi=10.1177/0885066609356164 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20018607  }}</ref>


==Carbon dioxide tension==
'''MathML'''
Carbon dioxide is a by-product of food metabolism and in high amounts has toxic effects including: [[dyspnea]], [[acidosis]] and [[altered consciousness]].<ref name="pmid2535633">{{cite journal| author=Adrogué HJ, Rashad MN, Gorin AB, Yacoub J, Madias NE| title=Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood. | journal=N Engl J Med | year= 1989 | volume= 320 | issue= 20 | pages= 1312–6 | pmid=2535633 | doi=10.1056/NEJM198905183202004 | pmc= | url= }}</ref>
:<math forcemathmode="mathml">E=mc^2</math>


;Arterial blood carbon dioxide tension
<!--'''PNG''' (currently default in production)
'''P<sub>a</sub>CO<sub>2</sub>''' — Partial pressure of carbon dioxide at sea level (765 mmHg) in arterial blood is between 35 mmHg and 45 mmHg.<ref name="pmid9794863">{{cite journal| author=Williams AJ| title=ABC of oxygen: assessing and interpreting arterial blood gases and acid-base balance. | journal=BMJ | year= 1998 | volume= 317 | issue= 7167 | pages= 1213–6 | pmid=9794863 | doi= 10.1136/bmj.317.7167.1213| pmc=1114160 | url= }}</ref>
:<math forcemathmode="png">E=mc^2</math>


;Venous blood carbon dioxide tension
'''source'''
'''P<sub>v</sub>CO<sub>2</sub>''' — Partial pressure of carbon dioxide at sea level in venous blood is between 40 mmHg and 50 mmHg.<ref name="pmid9794863"/>
:<math forcemathmode="source">E=mc^2</math> -->


==Carbon Monoxide tension==
<span style="color: red">Follow this [https://en.wikipedia.org/wiki/Special:Preferences#mw-prefsection-rendering link] to change your Math rendering settings.</span> You can also add a [https://en.wikipedia.org/wiki/Special:Preferences#mw-prefsection-rendering-skin Custom CSS] to force the MathML/SVG rendering or select different font families. See [https://www.mediawiki.org/wiki/Extension:Math#CSS_for_the_MathML_with_SVG_fallback_mode these examples].
;Arterial Carbon Monoxide tension (normal)
'''P<sub>a</sub>CO''' — Partial pressure of CO at sea level (765 mmHg) in arterial blood is approximately 0.02. It can be slightly higher in smokers and people living in dense urban areas.


==Significance==
==Demos==
The partial pressure of gas in blood is significant because it is directly related to ventilation and oxygenation.<ref name="pmid2661120">{{cite journal| author=Hansen JE| title=Arterial blood gases. | journal=Clin Chest Med | year= 1989 | volume= 10 | issue= 2 | pages= 227–37 | pmid=2661120 | doi= | pmc= | url= }}</ref>  When used alongside the pH balance of the blood the PaCO2 and HCO3 (and Lactate) lets the health care practitioner know what interventions need to be made, if any.<ref name="pmid2661120"/><ref name="pmid3144222">{{cite journal| author=Tobin MJ| title=Respiratory monitoring in the intensive care unit. | journal=Am Rev Respir Dis | year= 1988 | volume= 138 | issue= 6 | pages= 1625–42 | pmid=3144222 | doi= 10.1164/ajrccm/138.6.1625| pmc= | url= }}</ref>


== Equations ==
Here are some [https://commons.wikimedia.org/w/index.php?title=Special:ListFiles/Frederic.wang demos]:


=== Oxygen content ===
:<math>C_a O_2 = 1.36 * Hgb * \frac{S_a O_2}{100} + 0.0031 * P_a O_2</math>
The constant, 1.36, is the amount of oxygen (ml at 1 atmosphere) bound per gram of hemoglobin. The exact value of this constant varies from 1.34 to 1.39, depending on the reference and the way it is derived. The constant 0.0031 represents the amount of oxygen dissolved in plasma. The dissolved oxygen term is generally small relative to the hemoglobin-bound oxygen, but becomes significant at very high PaO2 (as in a hyperbaric chamber) or in severe anemia.<ref>{{cite web|url=http://www-users.med.cornell.edu/~spon/picu/calc/oxycont.htm|accessdate=7 October 2014}}</ref>


=== Oxygen saturation ===
* accessibility:
:<math> SO_2 = (\frac{23,400}{pO_2^3 + 150 pO_2} +1)^{-1}</math>
** Safari + VoiceOver: [https://commons.wikimedia.org/wiki/File:VoiceOver-Mac-Safari.ogv video only], [[File:Voiceover-mathml-example-1.wav|thumb|Voiceover-mathml-example-1]], [[File:Voiceover-mathml-example-2.wav|thumb|Voiceover-mathml-example-2]], [[File:Voiceover-mathml-example-3.wav|thumb|Voiceover-mathml-example-3]], [[File:Voiceover-mathml-example-4.wav|thumb|Voiceover-mathml-example-4]], [[File:Voiceover-mathml-example-5.wav|thumb|Voiceover-mathml-example-5]], [[File:Voiceover-mathml-example-6.wav|thumb|Voiceover-mathml-example-6]], [[File:Voiceover-mathml-example-7.wav|thumb|Voiceover-mathml-example-7]]
This is an estimation and does not account for differences in temperature, pH and concentrations of 2,3 DPG.<ref>Severinghaus, J. W. Simple, accurate equations for human blood O2 dissociation computations. J Appl Physiol. 46(3): 599-602. 1979.</ref>
** [https://commons.wikimedia.org/wiki/File:MathPlayer-Audio-Windows7-InternetExplorer.ogg Internet Explorer + MathPlayer (audio)]
** [https://commons.wikimedia.org/wiki/File:MathPlayer-SynchronizedHighlighting-WIndows7-InternetExplorer.png Internet Explorer + MathPlayer (synchronized highlighting)]
** [https://commons.wikimedia.org/wiki/File:MathPlayer-Braille-Windows7-InternetExplorer.png Internet Explorer + MathPlayer (braille)]
** NVDA+MathPlayer: [[File:Nvda-mathml-example-1.wav|thumb|Nvda-mathml-example-1]], [[File:Nvda-mathml-example-2.wav|thumb|Nvda-mathml-example-2]], [[File:Nvda-mathml-example-3.wav|thumb|Nvda-mathml-example-3]], [[File:Nvda-mathml-example-4.wav|thumb|Nvda-mathml-example-4]], [[File:Nvda-mathml-example-5.wav|thumb|Nvda-mathml-example-5]], [[File:Nvda-mathml-example-6.wav|thumb|Nvda-mathml-example-6]], [[File:Nvda-mathml-example-7.wav|thumb|Nvda-mathml-example-7]].
** Orca: There is ongoing work, but no support at all at the moment [[File:Orca-mathml-example-1.wav|thumb|Orca-mathml-example-1]], [[File:Orca-mathml-example-2.wav|thumb|Orca-mathml-example-2]], [[File:Orca-mathml-example-3.wav|thumb|Orca-mathml-example-3]], [[File:Orca-mathml-example-4.wav|thumb|Orca-mathml-example-4]], [[File:Orca-mathml-example-5.wav|thumb|Orca-mathml-example-5]], [[File:Orca-mathml-example-6.wav|thumb|Orca-mathml-example-6]], [[File:Orca-mathml-example-7.wav|thumb|Orca-mathml-example-7]].
** From our testing, ChromeVox and JAWS are not able to read the formulas generated by the MathML mode.


==See also==
==Test pages ==
* [[Fick's laws of diffusion]]
* [[Alveolar air equation]]


==References==
To test the '''MathML''', '''PNG''', and '''source''' rendering modes, please go to one of the following test pages:
<references/>
*[[Displaystyle]]
*[[MathAxisAlignment]]
*[[Styling]]
*[[Linebreaking]]
*[[Unique Ids]]
*[[Help:Formula]]


[[Category:Hematology]]
*[[Inputtypes|Inputtypes (private Wikis only)]]
[[Category:Respiratory therapy]]
*[[Url2Image|Url2Image (private Wikis only)]]
[[Category:Pulmonology]]
==Bug reporting==
If you find any bugs, please report them at [https://bugzilla.wikimedia.org/enter_bug.cgi?product=MediaWiki%20extensions&component=Math&version=master&short_desc=Math-preview%20rendering%20problem Bugzilla], or write an email to math_bugs (at) ckurs (dot) de .

Latest revision as of 22:52, 15 September 2019

This is a preview for the new MathML rendering mode (with SVG fallback), which is availble in production for registered users.

If you would like use the MathML rendering mode, you need a wikipedia user account that can be registered here [[1]]

  • Only registered users will be able to execute this rendering mode.
  • Note: you need not enter a email address (nor any other private information). Please do not use a password that you use elsewhere.

Registered users will be able to choose between the following three rendering modes:

MathML

E=mc2


Follow this link to change your Math rendering settings. You can also add a Custom CSS to force the MathML/SVG rendering or select different font families. See these examples.

Demos

Here are some demos:


Test pages

To test the MathML, PNG, and source rendering modes, please go to one of the following test pages:

Bug reporting

If you find any bugs, please report them at Bugzilla, or write an email to math_bugs (at) ckurs (dot) de .